Patient characteristics associated with risk of first hospital admission and readmission for acute exacerbation of chronic obstructive pulmonary disease (COPD) following primary care COPD diagnosis: a cohort study using linked electronic patient records

BMJ Open
L C HunterR M Hardie

Abstract

To investigate patient characteristics of an unselected primary care population associated with risk of first hospital admission and readmission for acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Retrospective open cohort using pseudonymised electronic primary care data linked to secondary care data. Primary care; Lothian (population approximately 800,000), Scotland. Data from 7002 patients from 72 general practices with a COPD diagnosis date between 2000 and 2008 recorded in their primary care record. Patients were followed up until 2010, death or they left a participating practice. First and subsequent admissions for AECOPD (International Classification of Diseases (ICD) 10 codes J44.0, J44.1 in any diagnostic position) after COPD diagnosis in primary care. 1756 (25%) patients had at least 1 AECOPD admission; 794 (11%) had at least 1 readmission and the risk of readmission increased with each admission. Older age at diagnosis, more severe COPD, low body mass index (BMI), current smoking, increasing deprivation, COPD admissions and interventions for COPD prior to diagnosis in primary care, and comorbidities were associated with higher risk of first AECOPD admission in an adjusted Cox proportional hazards...Continue Reading

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Citations

Dec 8, 2017·European Respiratory Review : an Official Journal of the European Respiratory Society·Corry-Anke BrandsmaWim Timens
Sep 22, 2018·The European Respiratory Journal·Victor Kim, Shawn D Aaron
Dec 10, 2019·The Clinical Respiratory Journal·Stanca-Patricia HogeaCristian Oancea
Oct 11, 2017·Current Opinion in Pulmonary Medicine·Manuel Suarez-BarceloGary T Ferguson
May 19, 2020·ERJ Open Research·Chia Wei Kong, Tom M A Wilkinson
Jan 22, 2019·International Journal of Clinical Practice·Elia Touma, Naiel Bisharat
Apr 20, 2018·American Journal of Respiratory and Critical Care Medicine·Alex J MackayJadwiga A Wedzicha
Nov 6, 2020·International Journal of Chronic Obstructive Pulmonary Disease·Christer JansonMagnus Ekström
Mar 12, 2021·ERJ Open Research·Marjan KerkhofDavid B Price
May 1, 2021·Journal of Clinical Medicine·Domingo Orozco-BeltránJose A Quesada
Nov 17, 2020·Respiratory Medicine·Chidiamara M NjokuBonnie J Bereznicki
Oct 1, 2019·American Journal of Preventive Medicine·Sericea Stallings-SmithAaron C Spaulding

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Software Mentioned

R
SPSS Statistics
SAS System
General Practice Administration System for Scotland ( GPASS )

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