PMID: 11921502Mar 30, 2002Paper

Patient compliance and persistence with anti-hyperglycemic therapy: evaluation of a population of type 2 diabetic patients

The Journal of International Medical Research
George E DaileyJ F Lian

Abstract

The persistence and compliance of type 2 diabetic patients to different regimens of anti-hyperglycemic therapy were assessed retrospectively. The pharmacy claims from a pharmacy benefit management organization were analysed from the third quarter of 1996 to the fourth quarter of 1999. Of the 23,400 patients enrolled and initiating anti-diabetic therapy, 85% started treatment with monotherapy, 9.5% with insulin alone, 4.1% with polytherapy and 1.3% with insulin plus another therapy. Monotherapy patients were characterized as receiving metformin, sulfonylurea or another agent. For the 1-year follow-up period, 70.5% of the metformin patients, 75.3% of the sulfonylurea patients and 86.8% of the polytherapy patients underwent no regimen modification (except discontinuation). For the patients who had no modification of their medication regimen, persistence with sulfonylurea or metformin monotherapy was 65% greater than with polytherapy over a 1-year period. Compliance with sulfonylurea or metformin monotherapy was 45% greater than with polytherapy.

References

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Citations

Jan 25, 2012·Advances in Therapy·Lawrence Blonde, Zinnia T San Juan
Jan 30, 2009·Diabetes, Obesity & Metabolism·C J Bailey, C Day
Feb 15, 2011·International Journal of Clinical Practice·C J Bailey, M Kodack
May 20, 2009·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Gretchen KimmickRajesh Balkrishnan
Mar 17, 2015·Current Medical Research and Opinion·Ronnie Aronson
Jul 28, 2010·Current Medical Research and Opinion·Gregory A NicholsJonathan B Brown
Aug 4, 2010·Clinical Therapeutics·Ayoade AdeyemiScott Strassels
Mar 11, 2004·Journal of the American Academy of Nurse Practitioners·David Bartels
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Aug 7, 2007·The American Journal of Medicine·Sripal BangaloreFranz H Messerli
Dec 20, 2014·Acta Diabetologica·Patrice SimardSylvie Perreault
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Oct 28, 2019·Chronic Illness·Anastasia-Stefania AlexopoulosMatthew J Crowley
Dec 16, 2010·Expert Review of Pharmacoeconomics & Outcomes Research·Thomas Wilke, Sabrina Müller

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