Patient doses in gamma-intracoronary radiotherapy: the Radiation Burden Assessment Study

International Journal of Radiation Oncology, Biology, Physics
Hubert ThierensYves Taeymans

Abstract

To determine accurately the radiation burden of both patients and staff from intracoronary radiotherapy (IRT) with (192)Ir and to investigate the importance of IRT in the patient dose compared with interventional X-rays. The Radiation Burden Assessment Study (RABAS) population consisted of 9 patients undergoing gamma-IRT after percutaneous transluminal coronary angioplasty and 14 patients undergoing percutaneous transluminal coronary angioplasty only as the control group. For each patient, the dose to the organs and tissues from the internal and external exposure was determined in detail by Monte Carlo N-particle simulations. Patient skin dose measurements with thermoluminescence dosimeters served as verification. Staff dosimetry was performed with electronic dosimeters, thermoluminescence dosimeters, and double film badge dosimetry. With respect to the patient dose from IRT, the critical organs are the thymus (58 mGy), lungs (31 mGy), and esophagus (27 mGy). The mean effective dose from IRT was 8 mSv. The effective dose values from interventional X-rays showed a broad range (2-28 mSv), with mean values of 8 mSv for the IRT patients and 13 mSv for the control group. The mean dose received by the radiotherapist from IRT was 4 mi...Continue Reading

References

Jun 12, 1997·The New England Journal of Medicine·P S TeirsteinP Tripuraneni
Jul 26, 2000·Health Physics·S BalterJ Moses
Feb 15, 2001·The New England Journal of Medicine·V VerinUNKNOWN Dose-Finding Study Group
Nov 1, 2002·Radiation Protection Dosimetry·L PermaL Conte

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Citations

Apr 2, 2010·ACS Applied Materials & Interfaces·Laura MazzocchettiMariastella Scandola

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