Patient experience of the informed consent process during acute myocardial infarction: a sub-study of the VALIDATE-SWEDEHEART trial

Trials
Anneli OlssonDavid Erlinge

Abstract

We aimed to assess the patient experience of informed consent (IC) during acute myocardial infarction (AMI) in a sub-study of the VALIDATE-SWEDEHEART trial. The original trial compared two anticoagulant agents in patients undergoing coronary intervention. A witnessed oral IC was required prior to randomization in patients with ST-segment elevation myocardial infarction, which was subsequently complemented with a written IC after percutaneous coronary intervention. Written consent was obtained before angiography in patients with non-ST-segment elevation myocardial infarction. The IC process in patients with AMI is under debate. Earlier trials in this population have required prospective consent before randomization. A trial published some years ago used deferred consent, but the patient experience of this process is poorly studied. A total of 414 patients who participated in the main trial were enrolled and asked the following questions: (1) Do you remember being asked to participate in a study? (2) How was your experience of being asked to participate; do you remember it being positive or negative? (3) Would you have liked more information about the study? (4) Do you think it would have been better if you were included in the s...Continue Reading

References

Jul 1, 1974·Social Science & Medicine·H L Smith
Aug 22, 2003·The New England Journal of Medicine·Henning R AndersenUNKNOWN DANAMI-2 Investigators
Sep 17, 2004·The Journal of Medicine and Philosophy·Anne Gammelgaard
Oct 22, 2013·JAMA : the Journal of the American Medical Association·UNKNOWN World Medical Association
Sep 27, 2014·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·David Zughaft, Jan Harnek
Jan 3, 2015·Acute Cardiac Care·Neal W DickertHabib Samady
Sep 4, 2015·BMJ : British Medical Journal·Liaquat R Johnson, Rangaswamy Siddaiah
Sep 12, 2015·Trials·Brennan C KahanSuzie Cro
Jan 1, 2017·Journal of Medical Ethics·Neal W DickertAlexandra E Fehr
Aug 29, 2017·The New England Journal of Medicine·David ErlingeStefan James
Apr 22, 2018·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Lauren KleinMichelle Biros
Mar 29, 2019·BMJ : British Medical Journal·Rafael Dal-RéShaun Treweek

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Citations

Jul 12, 2020·Nature Medicine·Rieke van der GraafMartine C de Vries

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Methods Mentioned

BETA
coronary artery bypass

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