Patient factors associated with receipt of combination antipsychotic drug therapy in the treatment of schizophrenia

Journal of Psychopharmacology
K P HayhurstS W Lewis

Abstract

Although discouraged in available treatment guidelines, combination antipsychotic prescribing (CAP) is a common practice in the treatment of schizophrenia. Patient characteristics may be associated with this type of treatment. A dataset (N = 363) derived from parallel randomised controlled trials was interrogated to identify factors associated with the receipt of CAP, and a logistic regression analysis was used to predict the occurrence of CAP. Significant predictors of CAP were longer illness, low global functioning score and high treatment adherence rating. Co-prescribed patients received a higher combined dose.

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Citations

Jul 23, 2013·Australasian Psychiatry : Bulletin of Royal Australian and New Zealand College of Psychiatrists·Licia Maiocchi, Elsa Bernardi

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