Patient-individualized boundary conditions for CFD simulations using time-resolved 3D angiography

International Journal of Computer Assisted Radiology and Surgery
Marco BoegelMarkus Kowarschik


Hemodynamic simulations are of increasing interest for the assessment of aneurysmal rupture risk and treatment planning. Achievement of accurate simulation results requires the usage of several patient-individual boundary conditions, such as a geometric model of the vasculature but also individualized inflow conditions. We propose the automatic estimation of various parameters for boundary conditions for computational fluid dynamics (CFD) based on a single 3D rotational angiography scan, also showing contrast agent inflow. First the data are reconstructed, and a patient-specific vessel model can be generated in the usual way. For this work, we optimize the inflow waveform based on two parameters, the mean velocity and pulsatility. We use statistical analysis of the measurable velocity distribution in the vessel segment to estimate the mean velocity. An iterative optimization scheme based on CFD and virtual angiography is utilized to estimate the inflow pulsatility. Furthermore, we present methods to automatically determine the heart rate and synchronize the inflow waveform to the patient's heart beat, based on time-intensity curves extracted from the rotational angiogram. This will result in a patient-individualized inflow velo...Continue Reading


Dec 15, 2005·IEEE Transactions on Medical Imaging·Matthew D FordDavid A Steinman
Feb 19, 2008·RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin·Christof KarmonikG Benndorf
Jul 22, 2008·Medical Image Analysis·I WaechterD J Hawkes
Sep 13, 2011·Physics in Medicine and Biology·M SpiegelArnd Doerfler
Oct 9, 2012·Medical Physics·Odile BonnefousDaniel Ruijters
Nov 30, 2012·Computational and Mathematical Methods in Medicine·Jürgen EndresArnd Dörfler
Apr 10, 2013·IEEE Transactions on Medical Imaging·Michael T ManhartJoachim Hornegger
Apr 27, 2013·AJNR. American Journal of Neuroradiology·B DavisC Mistretta
Jan 7, 2016·Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society·Marco BoegelArnd Doerfler


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