Patient-level glucose reporting: averages, episodes, or something in between?

Critical Care : the Official Journal of the Critical Care Forum
Susan S Braithwaite

Abstract

The article by Van Herpe and colleagues in the previous issue of Critical Care describes the glycemic penalty index (GPI), which weights both hyperglycemic and hypoglycemic blood glucose measurements commensurate to their clinically significant difference from target. Although certain adverse consequences result from isolated severe hyperglycemic episodes, several specific outcomes depend upon overall hyperglycemia. In contrast, although mortality has been related epidemiologically to overall low blood glucose, specific negative outcomes may depend upon isolated episodes. Capturing both hypoglycemia and hyperglycemia in a single index will be shown to be useful if the GPI enables us to better define insulin strategies, outcomes, and targets.

References

Jan 17, 2002·The New England Journal of Medicine·G van den BergheR Bouillon
Feb 11, 2003·Critical Care Medicine·Greet Van den BerghePeter Lauwers
May 29, 2003·The Journal of Thoracic and Cardiovascular Surgery·Anthony P FurnaryAlbert Starr
Aug 13, 2003·Archives of Internal Medicine·Nadya KaganskyHilla Knobler
Jan 24, 2006·Anesthesia and Analgesia·Anuj BhatiaIain Mackenzie
Feb 3, 2006·The New England Journal of Medicine·Greet Van den BergheRoger Bouillon
Aug 19, 2007·Journal of Hospital Medicine : an Official Publication of the Society of Hospital Medicine·Precil VargheseJonathan E Gottlieb
Aug 25, 2007·Critical Care Medicine·James S Krinsley, Aarti Grover
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Jan 11, 2008·The New England Journal of Medicine·Frank M BrunkhorstUNKNOWN German Competence Network Sepsis (SepNet)
Feb 28, 2008·Critical Care : the Official Journal of the Critical Care Forum·Tom Van HerpeGreet Van den Berghe

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