Patient perception and approval of faecal microbiota transplantation (FMT) as an alternative treatment option for obesity

Obesity Science & Practice
F GundlingW Schepp

Abstract

Fecal microbiota transplantation (FMT) represents a treatment option for some diseases, e.g. recurring Clostridium difficile-associated colitis. However, there is also evidence that FMT can be effective in treating obesity. This pilot study established the approval and willingness of obese patients to undergo FMT. We conducted a survey of adults with obesity using a questionnaire containing 21 both multiple choice and open questions was dispatched to a cohort of 101 persons with obesity. It included questions aiming at the process of FMT itself, donors as well as possible concerns. Additionally aspects of social background and disease activity were dealt with. The response rate amounted to 30.1% (n = 31). In our population, mean BMI was 40.5 kg/m2 while the vast majority already tried out treatment modalities to lose weight before. 25.8% of persons with obesity were aware of FMT. 62.1% were willing to undergo FMT if the donor was healthy and anonymous while only 6.9% clearly refused this option. Sixty preferred an anonymous donor or a person proposed by their doctor while colonoscopy was the preferred application by 76.7%. The absence of risks of the procedure (47.8%) formed the principal motivation while reduction of medicatio...Continue Reading

References

May 15, 1989·The Medical Journal of Australia·T J BorodyD Moore-Jones
Oct 27, 2004·Proceedings of the National Academy of Sciences of the United States of America·Fredrik BäckhedJeffrey I Gordon
Oct 4, 2005·Lancet·David W Haslam, W Philip T James
Jan 11, 2007·Proceedings of the National Academy of Sciences of the United States of America·Fredrik BäckhedJeffrey I Gordon
Sep 10, 2008·International Journal of Obesity : Journal of the International Association for the Study of Obesity·S H DuncanH J Flint
Jun 6, 2009·The Journal of Physiology·Peter J Turnbaugh, Jeffrey I Gordon
Jun 6, 2009·Obesity·Andreas SchwiertzPhilip D Hardt
May 6, 2011·The American Journal of Clinical Nutrition·Reiner JumpertzJonathan Krakoff
Dec 25, 2012·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·David B SarwerReneé H Moore
Apr 30, 2013·Inflammatory Bowel Diseases·Stacy A KahnDavid T Rubin
Sep 7, 2013·Science·Vanessa K RidauraJeffrey I Gordon
Oct 11, 2014·Techniques in Coloproctology·F GundlingI Iesalnieks
Jun 3, 2015·Open Forum Infectious Diseases·Neha Alang, Colleen R Kelly
Aug 16, 2016·Endocrinology and Metabolism Clinics of North America·David B Sarwer, Heather M Polonsky
Nov 24, 2016·European Journal of Gastroenterology & Hepatology·Jonas ZeitzMichael Scharl
Jan 19, 2017·The New England Journal of Medicine·Steven B Heymsfield, Thomas A Wadden
May 10, 2017·Journal of Crohn's & Colitis·Sudarshan ParamsothyNatalia Castaño-Rodríguez
Jun 7, 2017·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Jasmohan S BajajPatrick M Gillevet
Apr 25, 2018·Protein & Cell·Faming ZhangUNKNOWN FMT-standardization Study Group

❮ Previous
Next ❯

Citations

Jun 12, 2020·International Journal of Obesity : Journal of the International Association for the Study of Obesity·Béatrice S-Y ChoiAngelo Tremblay
Jun 30, 2019·Current Diabetes Reports·Judith Aron-WisnewskyMax Nieuwdorp
Dec 31, 2020·Journal of Clinical Nursing·Jessica GuilfoyleStéphane L Bouchoucha
Apr 10, 2021·Medicine in Microecology·Zoya GrigoryanAlison Bateman-House
Dec 29, 2021·The American Journal of Chinese Medicine·Zhengping PuGuorong Li

❮ Previous
Next ❯

Methods Mentioned

BETA
sedation

Related Concepts

Related Feeds

Bacteriotherapy (ASM)

Bacteriotherapy, also known as fecal transplantation, involves the transfer of stool from a healthy donor into the gastrointestinal tract for the purpose of treating recurrent C. difficile colitis. Here is the latest on bacteriotherapy.

Bacteriotherapy

Bacteriotherapy, also known as fecal transplantation, involves the transfer of stool from a healthy donor into the gastrointestinal tract for the purpose of treating recurrent C. difficile colitis. Here is the latest on bacteriotherapy.