Abstract
We administered a mixed-method survey to 1,661 patients in a large health system to assess preferences toward antihypertensive use for dementia prevention. If a specific antihypertensive medication was shown to prevent or delay dementia, the vast majority (>90%) of respondents currently taking an antihypertensive reported that they would be willing to take that specific antihypertensive starting as early as mid-life. Concerns reported were potential side effects, lack of evidence of effectiveness, blood pressure being normal or low, and medication cost. Analysis of free-text responses revealed themes of concerns regarding evidence of effectiveness and health priorities.
References
Aug 17, 1999·Archives of Neurology·Z GuoM Viitanen
May 30, 2001·Neurobiology of Aging·B A in't VeldM M Breteler
Oct 6, 2005·Qualitative Health Research·Hsiu-Fang Hsieh, Sarah E Shannon
Mar 15, 2006·Archives of Neurology·Ara S KhachaturianJohn C S Breitner
Jan 14, 2010·BMJ : British Medical Journal·Nien-Chen LiBenjamin Wolozin
Apr 9, 2014·Health Affairs·Lisa L Barnes, David A Bennett
Jun 29, 2014·BMC Public Health·Ben J SmithHenry Quach
Jan 13, 2016·Journal of Alzheimer's Disease : JAD·Daniel A NationUNKNOWN Alzheimer’s Disease Neuroimaging Initiative
Feb 3, 2016·Journal of Alzheimer's Disease : JAD·Emma L AshbySeth Love
Aug 21, 2016·Alzheimer's Research & Therapy·Penny A DacksHoward M Fillit
Dec 15, 2016·BMJ Open·Venexia M WalkerRichard M Martin
Jul 25, 2017·Lancet·Gill LivingstonNaaheed Mukadam
Dec 12, 2017·Journal of Alzheimer's Disease : JAD·Patrick G KehoeYoav Ben-Shlomo
Dec 20, 2017·Journal of Alzheimer's Disease : JAD·Whitney WhartonPatrick G Kehoe
Mar 23, 2018·Journal of Alzheimer's Disease : JAD·Patrick Gavin Kehoe
Feb 28, 2019·American Journal of Health Behavior·Zachary A MarcumEric B Larson
Citations
Mar 5, 2019·The Journal of Animal Ecology·Robin W WarneLydia Zeglin
Nov 7, 2020·Neurology·Jan Willem van DalenEdo Richard
Feb 6, 2020·Preventive Medicine Reports·Zachary A MarcumShelly L Gray
Sep 18, 2021·PloS One·Eleanor CurranVictoria J Palmer