Patient Preferences in the Treatment of Neovascular Age-Related Macular Degeneration: A Discrete Choice Experiment

Ophthalmology
Sabrina MuellerThomas Wilke

Abstract

The objective of our study was to investigate preferences of patients with neovascular age-related macular degeneration (nAMD) for different anti-vascular endothelial growth factor (VEGF) treatment schemes. We used a discrete choice experiment (DCE) design as part of a telephone interview. Patients with nAMD aged at least 50 years were included in the study. Telephone interviews were done between November 2012 and October 2013. In our DCE survey, we measured patient preferences toward specific levels of attributes that describe different options in the everyday intravitreal injection treatment setting: (1) treatment scheme; (2) change of visual acuity (VA); and (3) time the patient needs for each visit to the eye specialist. A total of 284 patients with nAMD with a mean age of 77.4±7.1 years (women: 59.9%) completed the DCE interviews. Of them, 22.9% had poor VA at study inclusion, 54.9% had moderate VA, and 14.1% had good VA; VA was not available for 8.1% of the patients. Generally, patients preferred the attribute levels "improvement in VA" and "short time per specialist visit." The results for the attribute "treatment scheme" were inconclusive because none of the attribute levels (injections every 4 weeks, every 8 weeks, and...Continue Reading

References

Oct 20, 2005·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Jochen ZwerinaGeorg Schett
Mar 1, 2008·Zeitschrift für Rheumatologie·J Zwerina
Apr 30, 2011·The New England Journal of Medicine·UNKNOWN CATT Research GroupGlenn J Jaffe
Dec 14, 2011·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Thomas WilkeDonald E Morisky
Jan 23, 2013·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·F Reed JohnsonJohn F P Bridges
Jun 15, 2013·Clinical Interventions in Aging·Angie H C Fong, Timothy Y Y Lai
Jul 19, 2013·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Katharina M DroegeSascha Fauser
Jan 16, 2014·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Armin Wolf, Anselm Kampik
Jul 10, 2014·PharmacoEconomics·Michael D ClarkEsther W de Bekker-Grob

❮ Previous
Next ❯

Citations

Feb 3, 2016·Molecular Pharmaceutics·Nickisa HodgsonJiawei Wang
Aug 10, 2019·Clinical & Experimental Ophthalmology·Thomas Chengxuan LuLisa Keay
Aug 5, 2017·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·S MüllerT Wilke
Mar 19, 2020·Patient Preference and Adherence·Annette EidamJürgen M Bauer
May 4, 2020·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Jae Hui KimDong Won Lee
Jun 3, 2018·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Marie-Christine BruenderChristoph Ehlken
Jan 9, 2020·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·J Stasch-BouwsD Pauleikhoff
Jun 24, 2020·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Christoph EhlkenAlexander K Schuster
Jun 20, 2020·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Jae Hui KimDong Won Lee
Apr 8, 2020·Patient Preference and Adherence·Fraence HardtstockShirley V Sylvester
Jan 7, 2021·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Ji Hyun LeeDong Won Lee
Apr 27, 2021·Expert Opinion on Biological Therapy·Lorenzo Ferro DesideriMassimo Nicolò
Jul 24, 2021·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Ulrich KellnerTina Schick
Jul 19, 2021·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Ling YeungSan-Ni Chen

❮ Previous
Next ❯

Related Concepts

Related Feeds

Arterial-Venous in Development & Disease

Arterial-venous development may play a crucial role in cardiovascular diseases. Here is the latest research.