Patient-reported factors associated with reengagement among HIV-infected patients disengaged from care in East Africa

AIDS
Carol S CamlinEast Africa International Epidemiologic Databases to Evaluate AIDS (EA-IeDEA) Consortium

Abstract

Engagement in care is key to successful HIV treatment in resource-limited settings; yet little is known about the magnitude and determinants of reengagement among patients out of care. We assessed patient-reported reasons for not returning to clinic, identified latent variables underlying these reasons, and examined their influence on subsequent care reengagement. We used data from the East Africa International Epidemiologic Databases to Evaluate AIDS to identify a cohort of patients disengaged from care (>3 months late for last appointment, reporting no HIV care in preceding 3 months) (n = 430) who were interviewed about reasons why they stopped care. Among the 399 patients for whom follow-up data were available, 104 returned to clinic within a median observation time of 273 days (interquartile range: 165-325). We conducted exploratory and confirmatory factor analyses (EFA, CFA) to identify latent variables underlying patient-reported reasons, then used these factors as predictors of time to clinic return in adjusted Cox regression models. EFA and CFA findings suggested a six-factor structure that lent coherence to the range of barriers and motivations underlying care disengagement, including poverty, transport costs, and inte...Continue Reading

References

Mar 1, 1990·Psychological Bulletin·P M Bentler
Jul 28, 2006·British Journal of Health Psychology·Margaret A ChesneySusan Folkman
Apr 21, 2007·Tropical Medicine & International Health : TM & IH·Heiko KarcherGundel Harms
May 8, 2007·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Laura W Cheever
Aug 2, 2008·Bulletin of the World Health Organization·Martin W G BrinkhofUNKNOWN ART-LINC, IeDEA
Nov 1, 2008·BMC Medical Research Methodology·Ian Shrier, Robert W Platt
Aug 4, 2011·Epidemiology·Johannes TextorSven Knüppel

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