Patient-reported outcome measurement in community-acquired pneumonia: feasibility of routine application in an elderly hospitalized population

Pilot and Feasibility Studies
Melanie LloydHarin A Karunajeewa

Abstract

Community-acquired pneumonia (CAP) is a leading cause of morbidity and mortality worldwide, but few studies have evaluated the feasibility of routine patient-reported outcome measures (PROMs) in this illness. This study investigates the feasibility and limitations of three credible PROM instruments in a representative hospitalized cohort to identify potential barriers to routine application. A sample of multimorbid hospitalized subjects meeting a standardized CAP definition was recruited. Demographic and clinical data of those able and unable to participate in PROM assessment were compared. The EQ-5D-5L, CAP-Sym 18 Questionnaire, and Late-Life Function and Disability Instrument (LLFDI) were administered (via face-to-face interview) at admission and discharge and (via phone interview or mail) at 30 and 90 days post-discharge. Feasibility measures included the proportion of individuals able to participate in assessment, attrition rates, data completeness, and instrument completion times. Scores at admission and 30 days post-discharge were examined for association with age. Of 82 subjects screened, 44 (54%) participated. Cognitive impairment (n = 12, 15%) commonly precluded participation. Seventeen (39%) participants were lost to ...Continue Reading

Associated Clinical Trials

References

Jul 1, 1997·Journal of General Internal Medicine·J P MetlayD E Singer
Aug 1, 1997·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·W R LenderkingS Hammer
Mar 23, 2002·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Stephen M HaleyJacqueline Ashba
May 22, 2002·Psychosomatic Medicine·Rebecca G LogsdonLinda Teri
Jun 18, 2002·Chest·Gilles ClermontMichael R Pinsky
Feb 7, 2003·The European Respiratory Journal·A TorresG Höffken
Aug 7, 2003·The Lancet Infectious Diseases·Gavin D BarlowDilip Nathwani
Sep 13, 2003·Chest·Linda M MundyWilliam Claiborne Dunagan
Sep 3, 2004·Journal of the American Geriatrics Society·Stephen P SayersRoger A Fielding
Sep 29, 2004·Journal of the American Geriatrics Society·Olga H TorresGuillermo Vázquez
Oct 8, 2004·European Journal of Epidemiology·Vicki KristmanPierre Côté
Dec 13, 2006·Journal of Clinical Epidemiology·Caroline B TerweeHenrica C W de Vet
Feb 6, 2010·American Journal of Respiratory and Critical Care Medicine·Dominic SnijdersWim G Boersma
Apr 12, 2011·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·M HerdmanX Badia
Jul 17, 2012·JAMA : the Journal of the American Medical Association·Mary E TinettiCynthia M Boyd
Nov 28, 2012·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·M F JanssenJan Busschbach
Apr 2, 2015·The New England Journal of Medicine·Douwe F PostmaUNKNOWN CAP-START Study Group
Jul 15, 2015·The New England Journal of Medicine·Seema JainUNKNOWN CDC EPIC Study Team
Nov 11, 2015·Health and Quality of Life Outcomes·Norma B BulamuJulie Ratcliffe
Dec 17, 2015·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·George H TalbotUNKNOWN Biomarkers Consortium of the Foundation for the National Institutes of Health CABP-ABSSSI and HABP-VABP Project Teams
Mar 16, 2017·BMC Infectious Diseases·Marie-Josée J MangenG Ardine de Wit
Aug 24, 2017·Health Economics·Nancy J DevlinBen van Hout
Nov 19, 2017·Respirology : Official Journal of the Asian Pacific Society of Respirology·Jane Hadfield, Lesley Bennett
Feb 6, 2018·Health and Quality of Life Outcomes·Luiz Flavio AndradeGérard de Pouvourville

❮ Previous
Next ❯

Citations

Jul 1, 2020·Journal of Evaluation in Clinical Practice·Richard A YoungCarmel M Martin

❮ Previous
Next ❯

Clinical Trials Mentioned

NCT02835040

Software Mentioned

REDCap
Sym
Stata
SWAT
CAP

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.