Patient-reported Outcomes across Categories of Juvenile Idiopathic Arthritis

The Journal of Rheumatology
Alysha J TaxterPamela F Weiss

Abstract

Although there is increasing reliance on patient-reported outcomes (PRO) for disease management, there is little known about the differences in PRO across juvenile idiopathic arthritis (JIA) categories. The purpose of our study was to assess PRO across JIA categories, including pain, quality of life, and physical function, and to determine clinical factors associated with differences in these measures across categories. This was a longitudinal cohort study of patients with JIA at a tertiary care pediatric rheumatology clinic. Subjects, PRO, and clinical variables were identified by querying the electronic medical record. Mixed-effects regression assessed pain, quality of life, and function. Subjects with enthesitis-related arthritis (ERA) and undifferentiated JIA had significantly more pain, poorer quality of life, and poorer physical function. The ERA and undifferentiated JIA categories, physician's global disease activity assessment, female sex, and nonsteroidal antiinflammatory drug use were significantly associated with more pain, poorer quality of life, and poorer function. In models limited to ERA, female sex and tender enthesis count were significant predictors of decreased function. ERA and undifferentiated JIA categori...Continue Reading

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Citations

May 3, 2016·Rheumatic Diseases Clinics of North America·Aimee O HershElissa R Weitzman
Dec 19, 2017·Modern Rheumatology·Heikki RelasSilja Kosola
Jul 17, 2019·The Journal of Rheumatology·Lisa BuckleyJon M Burnham
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Jul 30, 2020·Expert Opinion on Pharmacotherapy·Achille MarinoRolando Cimaz
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Feb 12, 2019·Arthritis Care & Research·Dax G RumseyUNKNOWN Research in Arthritis in Canadian Children Emphasizing Outcomes Investigators
Jul 17, 2019·Pediatric Rheumatology Online Journal·Ellen NordalUNKNOWN Nordic Study Group of Pediatric Rheumatology (NoSPeR)
Jun 23, 2018·Rheumatology·Evert H Pieter van DijkhuizenAlberto Martini
Oct 23, 2020·Arthritis Care & Research·Anna E Greer, Maura D Iversen
Nov 20, 2019·Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases·Rebecca TrachtmanLisa A Mandl
Jun 18, 2021·Frontiers in Medicine·Corinne FisherLucy R Wedderburn
Jul 14, 2021·Current Rheumatology Reports·Hemalatha SrinivasaluChristopher Redmond

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