Patient-reported Outcomes from A National, Prospective, Observational Study of Emergency Department Acute Pain Management With an Intranasal Nonsteroidal Anti-inflammatory Drug, Opioids, or Both

Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine
Charles V PollackKnox H Todd

Abstract

Patient compliance and satisfaction with analgesics prescribed after emergency department (ED) care for acute pain are poorly understood, largely because of the lack of direct patient follow-up with the ED provider. Our objective was to compare patient satisfaction with three analgesia regimens prescribed for post-ED care-a nasally administered nonsteroidal anti-inflammatory drug (NSAID), an opioid, or combination therapy-by collecting granular follow-up on analgesic use, pain scores, side effects, work activity levels, and overall satisfaction directly from patients. We designed a prospective registry linking ED assessment and analgesic management for acute pain of specific musculoskeletal or visceral etiologies with self-reported automated telephonic follow-up daily for the 4 days post-ED discharge. Patients were prescribed a specific NSAID (SPRIX, ketorolac tromethamine for nasal instillation) only, an oral opioid only, or both with the opioid clearly defined as rescue therapy, at the ED provider's discretion. There were 824 evaluable subjects. Maximum pain scores improved day to day more effectively with a ketorolac-based approach. Self-reported rates of return to work and work effectiveness were higher with SPRIX than with...Continue Reading

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References

May 1, 1978·The American Journal of Medicine·R P KimberlyP H Plotz
Apr 1, 1996·Annals of Emergency Medicine·K H ToddR Bonacci
Sep 18, 1997·Journal of Pain and Symptom Management·B S ShapiroG Heidrich
Feb 7, 2001·JAMA : the Journal of the American Medical Association·D E JoransonJ L Dahl
Jul 3, 2002·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Syed R AhmadJulie Beitz
Mar 25, 2004·Annals of Emergency Medicine·Timothy Rupp, Kathleen A Delaney
May 26, 2004·Pain·Margaret A Caudill-SlosbergSteven Woloshin
Apr 5, 2005·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Catherine A MarcoAlisa Roberts
Apr 15, 2005·Emergency Medicine Clinics of North America·Knox H Todd
Nov 23, 2006·Annals of Emergency Medicine·David J HewittUNKNOWN CAPSS-216 Study Investigators
Feb 20, 2007·The Journal of Pain : Official Journal of the American Pain Society·Knox H ToddUNKNOWN PEMI Study Group
Jan 3, 2008·JAMA : the Journal of the American Medical Association·Mark J PletcherRalph Gonzales
Jul 15, 2009·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Colin BrownLincoln Bynum
Sep 1, 2009·Pharmacoepidemiology and Drug Safety·Denise BoudreauConstance Weisner
Jan 5, 2010·Annals of Emergency Medicine·David F BaehrenPeter Akpunonu
Jun 19, 2010·Current Medical Research and Opinion·Neil SinglaColin Brown
Nov 19, 2010·The New England Journal of Medicine·Susan Okie
Apr 7, 2011·JAMA : the Journal of the American Medical Association·Nora D VolkowSusan R B Weiss
Jan 25, 2012·TheScientificWorldJournal·Ippokratis PountosPeter V Giannoudis
Feb 22, 2012·American Journal of Medical Quality : the Official Journal of the American College of Medical Quality·Marie N HannaPeter Pronovost
Mar 27, 2012·Translational Behavioral Medicine·Gregory Lieberman, Magdalena R Naylor
Sep 27, 2012·Annals of Emergency Medicine·Stephen V CantrillUNKNOWN American College of Emergency Physicians Opioid Guideline Writing Panel
Nov 28, 2012·International Journal of Clinical Practice. Supplement·I Bjarnason
May 3, 2013·Advanced Emergency Nursing Journal·Dian Dowling Evans, Christine Gisness
Jul 16, 2013·The Journal of Emergency Medicine·Hemangini C Bhakta, Catherine A Marco
Sep 13, 2013·Medical Care·Matthew DaubresseG Caleb Alexander
Jan 8, 2014·Journal of Pharmacy & Pharmaceutical Sciences : a Publication of the Canadian Society for Pharmaceutical Sciences, Société Canadienne Des Sciences Pharmaceutiques·Sam HarirforooshFakhreddin Jamali
Jul 17, 2014·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Kate Traynor
Jul 23, 2014·Current Medical Research and Opinion·Allan GibofskyClarence L Young
Feb 24, 2015·Journal of Clinical Epidemiology·Peter C Austin, Ewout W Steyerberg

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Citations

Nov 3, 2016·The American Journal of Emergency Medicine·Reuben J StrayerLewis S Nelson
Jun 8, 2017·The Clinical Journal of Pain·Christopher G GhariboClarence Young
Jan 17, 2020·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Howard S KimDavid Cella
Jan 27, 2019·Journal of Orthopaedic Trauma·Joseph R HsuUNKNOWN Orthopaedic Trauma Association Musculoskeletal Pain Task Force
Mar 4, 2021·The American Journal of Emergency Medicine·Stephanie A EuckerCaroline Freiermuth
Nov 26, 2021·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Daniel S TszePeter S Dayan

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