Patient Safety and Pro Re Nata Prescription and Administration: A Systematic Review

Pharmacy : Journal of Pharmacy, Education and Practice
Mojtaba VaismoradiSue Jordan

Abstract

PRN is the acronym for 'pro re nata,' written against prescriptions whose administration should be based on patients' needs, rather than at set times. The aim of this systematic review was to explore safety issues and adverse events arising from PRN prescription and administration. Electronic databases including Scopus, PubMed [including Medline], Embase, Cinahl, Web of Science and ProQuest were systematically searched to retrieve articles published from 2005 to 2017. we included all randomized controlled trials (RCTs) and studies with comparison groups, comparing PRN prescription and administration with scheduled administration, where safety issues and adverse events were reported. The authors independently assessed titles, abstracts and full-texts of retrieved studies based on inclusion criteria and risk of bias. Results were summarised narratively. The search identified 7699 articles. Title, abstract and full-text appraisals yielded 5 articles. The included studies were RCTs with one exception, a pre-test post-test experimental design. Patient populations, interventions and outcomes varied. Studies compared patient-controlled or routine administration with PRN and one trial assessed the effect of a practice guideline on impl...Continue Reading

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Citations

Oct 28, 2018·Pharmacy : Journal of Pharmacy, Education and Practice·Mojtaba Vaismoradi
Nov 30, 2019·Pharmacy : Journal of Pharmacy, Education and Practice·Mojtaba VaismoradiSue Jordan
Oct 10, 2020·The American Journal of Hospice & Palliative Care·Fatima Ropri, Carol S Weisse
Oct 30, 2020·Pharmacy : Journal of Pharmacy, Education and Practice·Mojtaba VaismoradiManela Glarcher
Sep 22, 2021·BMJ Open Quality·Samantha Leigh RossSuzanne Grant

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Methods Mentioned

BETA
PCA

Software Mentioned

Embase
Web
Cinahl
Scopus
Science
of
ProQuest

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