Patient-specific computational models to support interventional procedures: a case study of complex aortic re-coarctation

EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
Daria CosentinoSilvia Schievano

Abstract

We report the application of patient-specific computational models to plan the treatment of complex aortic re-coarctation (rCoA) with a proximal aberrant right subclavian artery in a patient who had previously undergone bare metal stenting. Clinically acquired images were used to set up patient-specific computational models for finite element (FE) and fluid dynamics (CFD) analyses. The 3D geometry was reconstructed from computed tomography and echocardiography images. Computer-generated deployment of a CP covered stent (NuMED, Hopkinton, NY, USA) at different diameters was tested using FE simulations. CFD analyses based on preoperative magnetic resonance flow measurements allowed assessment of rCoA pressure relief and right subclavian artery perfusion in the different scenarios. The simulations suggested an expansion diameter for the CP stent (8 zigs, length=28 mm) of between 16 and 18 mm to relieve the obstruction, cover the aneurysm and maintain satisfactory flow to the right subclavian artery. Following the modelling study, a 16 mm CP covered stent was successfully implanted. Patient-specific models can be successfully used to plan re-stenting of complex rCoA, showing the benefits of integrating computational techniques into...Continue Reading

References

Dec 4, 2009·Briefings in Bioinformatics·Maxwell Lewis Neal, Roy Kerckhoffs

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Citations

Dec 30, 2017·Interface Focus·Claudio CapelliSilvia Schievano
May 16, 2018·JRSM Cardiovascular Disease·Barbara Eu BurkhardtTarique Hussain
Jul 2, 2016·Journal of Biomechanical Engineering·David C WendellJohn F LaDisa
Jun 20, 2020·Scientific Reports·Giorgia M BosiSilvia Schievano
Sep 25, 2017·Trends in Biotechnology·Amanda RandlesJane A Leopold

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