Patient specific implants for amputation prostheses: design, manufacture and analysis

Veterinary and Comparative Orthopaedics and Traumatology : V.C.O.T
P DevasconcellosA Bandyopadhyay

Abstract

To design, manufacture and analyze custom implants with functional gradation in macrostructure for attachment of amputation prostheses. The external shape of the implant was designed by extracting geometrical data of canine cadavers from computed tomography (CT) scans to suit the bone cavity. Three generations of implant designs were developed and were optimized with the help of fit/fill and mechanical performance of implant-cadaver bone assembly using CT analysis and compression testing, respectively. A final optimized, custom Ti6Al4V alloy amputation implant, with approximately 25% porosity in the proximal region and approximately zero percent porosity in the distal region, was fabricated using Laser Engineered Net Shaping (LENS™)--a laser based additive manufacturing technology. The proposed design changes in the second generation designs, in terms of refining thresholds, increased the average fill of the bone cavity from 58% to 83%. Addition of a flange between the stem and the head in the second generation designs resulted in more than a seven-fold increase in the compressive load carrying capacity of the assembly. Application of LENS™ in the fabrication of present custom fit Ti6Al4V alloy implants enabled incorporation of...Continue Reading

References

Jun 1, 1988·Journal of Biomedical Materials Research·B ChehroudiD M Brunette
Apr 1, 1980·Prosthetics and Orthotics International·S W Levy
Oct 1, 1996·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·H KrögerO Suomalainen
Apr 29, 1998·The Orthopedic Clinics of North America·B A MasriC P Duncan
Feb 25, 2000·Journal of the American Academy of Dermatology·C C LyonM H Beck
Nov 28, 2000·Audiology : Official Organ of the International Society of Audiology·K M Holgers
Jul 4, 2001·Disability and Rehabilitation·P GallagherM Maclachlan
Feb 28, 2002·Prosthetics and Orthotics International·K Hagberg, R Brånemark
Oct 24, 2003·Prosthetics and Orthotics International·J SullivanS Sooriakumaran
Dec 9, 2003·Journal of Biomedical Materials Research. Part a·Karin A HingPeter A Revell
Jul 19, 2005·Clinical Biomechanics·Christian GötzeLars Hackenberg
Nov 12, 2005·Prosthetics and Orthotics International·K HagbergR Brånemark
Jan 21, 2006·Biomaterials·Garrett RyanDimitrios Panagiotis Apatsidis
Apr 19, 2006·Biomaterials·Catherine J PendegrassGordon W Blunn
May 29, 2007·Acta Biomaterialia·B Vamsi KrishnaAmit Bandyopadhyay
Jul 14, 2007·Acta Biomaterialia·Weichang XueSusmita Bose
Nov 3, 2007·Medical Engineering & Physics·Winson C C LeeRickard Brånemark
Dec 7, 2007·Acta Biomaterialia·B Vamsi KrishnaAmit Bandyopadhyay
Feb 26, 2008·Archives of Physical Medicine and Rehabilitation·Kathryn Ziegler-GrahamRon Brookmeyer
Apr 29, 2009·Acta Biomaterialia·Vamsi Krishna BallaAmit Bandyopadhyay
Nov 17, 2009·Acta Biomaterialia·Amit BandyopadhyayNeal M Davies
Nov 26, 2009·Acta Biomaterialia·Vamsi Krishna BallaAmit Bandyopadhyay
Feb 6, 2010·Acta Biomaterialia·Vamsi Krishna BallaAmit Bandyopadhyay
Mar 24, 2010·Annals of Biomedical Engineering·P K TomaszewskiG J Verkerke
Jan 7, 2011·The Journal of Bone and Joint Surgery. American Volume·Kelly A JeansLori A Karol

❮ Previous
Next ❯

Citations

Jul 13, 2012·Veterinary and Comparative Orthopaedics and Traumatology : V.C.O.T·K A Johnson
Apr 5, 2013·Journal of Biomedical Materials Research. Part a·M Pitkin
Jun 22, 2017·Veterinary and Comparative Orthopaedics and Traumatology : V.C.O.T·Andrew PhillipsArthur House
Aug 23, 2017·Journal of the American Veterinary Medical Association·Jonathan P BrayIan W M Brown

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA
Su-Zhen SunRong-Fu Shi
Journal of Applied Biomaterials & Biomechanics : JABB
María Dolores PazBetty León
© 2021 Meta ULC. All rights reserved