Patient-specific simulation of guidewire deformation during transcatheter aortic valve implantation

International Journal for Numerical Methods in Biomedical Engineering
Phuoc VyStéphane Avril

Abstract

Transcatheter aortic valve implantation is a recent mini-invasive procedure to implant an aortic valve prosthesis. Prosthesis positioning in transcatheter aortic valve implantation appears as an important aspect for the success of the intervention. Accordingly, we developed a patient-specific finite element framework to predict the insertion of the stiff guidewire, used to position the aortic valve. We simulated the guidewire insertion for 2 patients based on their pre-operative CT scans. The model was designed to primarily predict the position and the angle of the guidewires in the aortic valve, and the results were successfully compared with intraoperative images. The present paper describes extensively the numerical model, which was solved by using the ANSYS software with an implicit resolution scheme, as well as the stabilization techniques which were used to overcome numerical instabilities. We performed sensitivity analysis on the properties of the guidewire (curvature angle, curvature radius, and stiffness) and the conditions of insertion (insertion force and orientation). We also explored the influence of the model parameters. The accuracy of the model was quantitatively evaluated as the distance and the angle differenc...Continue Reading

References

May 1, 1995·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Y WangR L Ehman
Feb 2, 2008·Journal of the American College of Cardiology·Rachid ZegdiJean-Noël Fabiani
May 13, 2009·Cardiovascular and Interventional Radiology·Tim Frederik WeberHendrik von Tengg-Kobligk
Sep 26, 2009·JACC. Cardiovascular Interventions·Jean-Bernard MassonJohn G Webb
Dec 25, 2009·International Journal of Computer Assisted Radiology and Surgery·Sebastian SchaferKenneth R Hoffmann
May 11, 2010·Medical Image Analysis·P MarkeljF Pernuš
Oct 22, 2010·The New England Journal of Medicine·Martin B LeonUNKNOWN PARTNER Trial Investigators
Feb 9, 2011·Computer Methods in Biomechanics and Biomedical Engineering·Vincent LubozFernando Bello
Jun 7, 2011·The New England Journal of Medicine·Craig R SmithUNKNOWN PARTNER Trial Investigators
Aug 4, 2011·Expert Review of Cardiovascular Therapy·Joanne ShannonAntonio Colombo
Dec 14, 2011·Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists·Gareth J HarrisonRichard G McWilliams
Feb 5, 2013·Journal of the American College of Cardiology·Philippe GénéreuxMartin B Leon
Feb 14, 2013·Computer Methods in Biomechanics and Biomedical Engineering·F AuricchioA Reali
Apr 23, 2013·JACC. Cardiovascular Interventions·Henrique Barbosa RibeiroJosep Rodés-Cabau
Apr 17, 2014·Biomechanics and Modeling in Mechanobiology·Qian WangWei Sun
May 14, 2014·Annual Review of Biomedical Engineering·Wei SunThuy Pham
Jul 12, 2014·Journal of the American College of Cardiology·George C M SiontisStephan Windecker
Jul 1, 2017·Journal of the American College of Cardiology·Vincent AuffretUNKNOWN FRANCE TAVI Investigators

❮ Previous
Next ❯

Citations

Jun 23, 2020·Computers in Biology and Medicine·Yasser AbuoufMahmoud Ahmed

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.