"Patient-specific validation of deformable image registration in radiation therapy: Overview and caveats"

Medical Physics
Chiara PaganelliG Baroni

Abstract

Over the last few decades, deformable image registration (DIR) has gained popularity in image-guided radiation therapy for a number of applications, such as contour propagation, dose warping, and accumulation. Although this raises promising perspectives for the improvement of treatment outcomes and quality of radiotherapy clinical practice, the variety of proposed DIR algorithms, combined with the lack of an effective quantitative quality control metric of the registration, is slowing the transfer of DIR into the clinical routine. Recently, a task group (AAPM TG132) report was published outlining the essential aspects of DIR for image guidance in radiotherapy. However, an accurate and efficient patient-specific validation is not yet defined, and appropriate metrics should be identified to achieve the definition of both geometric and dosimetric accuracy. In this respect, the use of a dense set of anatomical landmarks, along with additional evaluations on contours or deformation field analysis, are likely to drive patient-specific DIR validation in clinical image-guided radiotherapy applications to account for geometric inaccuracies. Automatic and efficient strategies able to provide spatial information of DIR uncertainties and t...Continue Reading

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Jul 19, 2019·Medical Physics·Yabo FuDeshan Yang
Oct 28, 2019·The British Journal of Radiology·Francesca AlbertiniAntony Lomax
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Nov 18, 2021·Journal of Applied Clinical Medical Physics·Pawel SiciarzEric Van Uytven
Oct 19, 2020·Zeitschrift für medizinische Physik·Giorgia MeschiniGuido Baroni

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