Patient-ventilator asynchrony in preterm infants on nasal intermittent positive pressure ventilation

Archives of Disease in Childhood. Fetal and Neonatal Edition
Cornelia G de WaalGerard J Hutten

Abstract

To describe the incidence of patient-ventilator asynchrony and different types of asynchrony in preterm infants treated with non-synchronised nasal intermittent positive pressure ventilation (nIPPV). An observational study was conducted including preterm infants born with a gestational age (GA) less than 32 weeks treated with non-synchronised nIPPV. During 1 hour, spontaneous breathing was measured with transcutaneous electromyography of the diaphragm simultaneous with ventilator inflations. An asynchrony index (AI), a percentage of asynchronous breaths, was calculated and the incidence of different types of inspiratory and expiratory asynchrony were reported. Twenty-one preterm infants with a mean GA of 26.0±1.2 weeks were included in the study. The mean inspiratory AI was 68.3%±4.7% and the mean expiratory AI was 67.1%±7.3%. Out of 5044 comparisons of spontaneous inspirations and mechanical inflations, 45.3% of the mechanical inflations occurred late, 23.3% of the mechanical inflations were early and 31.4% of the mechanical inflation were synchronous. 40.3% of 5127 expiratory comparisons showed an early termination of ventilator inflations, 26.7% of the mechanical inflations terminated late and 33.0% mechanical inflations ter...Continue Reading

References

Dec 1, 1977·Early Human Development·H F PrechtlM J O'Brien
Jun 14, 2000·Journal of Applied Physiology·E J MaarsinghW M van Aalderen
Mar 31, 2007·Clinics in Perinatology·Sherry E Courtney, Keith J Barrington
Feb 19, 2008·Pediatrics International : Official Journal of the Japan Pediatric Society·Corrado MorettiPatrizia Colarizi
Oct 7, 2010·Pediatric Research·Hung-Yang ChangEduardo Bancalari
Feb 22, 2011·Archives of Disease in Childhood. Fetal and Neonatal Edition·L S OwenP G Davis
Jul 19, 2013·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Laurence VignauxPeter C Rimensberger
Oct 18, 2013·Critical Care : the Official Journal of the Critical Care Forum·Christer SinderbyJennifer Beck
Jun 20, 2014·Archives of Disease in Childhood. Fetal and Neonatal Edition·L S OwenP G Davis
Oct 17, 2014·Archives of Disease in Childhood. Fetal and Neonatal Edition·Camilla GizziRocco Agostino
Dec 3, 2015·Pediatrics·Eric C Eichenwald, UNKNOWN Committee on Fetus and Newborn, American Academy of Pediatrics
Feb 24, 2016·Seminars in Fetal & Neonatal Medicine·Howard SteinMichael Dunn
Nov 14, 2016·Clinics in Perinatology·Markus WaitzBrigitte Lemyre

❮ Previous
Next ❯

Citations

Nov 11, 2020·Pediatric Pulmonology·Corrado MorettiCamilla Gizzi

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved