Patients' perceptions and illness severity at start of antidepressant treatment in general practice

The International Journal of Pharmacy Practice
Erica C G van GeffenRolf van Hulten

Abstract

Patients' perceptions are important to consider when trying to understand why patients often do not follow prescriptions for antidepressant treatment. This study aimed to investigate the influence of patients' perceptions and illness severity at the start on antidepressant-medication-taking behaviour. Eighteen community pharmacies in the Netherlands participated in this 6-month follow-up study. One hundred and ten patients presenting a first antidepressant prescription, prescribed by a general practitioner (GP), were included. A questionnaire was completed at inclusion, after 6 and 26 weeks. Of all 110 patients, eight (7.3%) did not initiate drug taking, 32 (29.1%) discontinued use, six (5.5%) switched to different antidepressant medication, and 64 (58.2%) continued on the same antidepressant during follow-up. Compared to continuers, non-initiators had lower belief scores for impact of illness (P = 0.044), perceived norm GP (P < 0.001), intention to take medication (P < 0.001), and attitude towards medication (P = 0.004). Furthermore, non-initiators were less severely depressed (P = 0.024). Discontinuers and continuers did not differ in illness severity at inclusion. However, discontinuers more often reported a non-specific rea...Continue Reading

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Citations

Jul 16, 2014·Patient Education and Counseling·Sophie LiekensVeerle Foulon
Oct 23, 2012·Revista de psiquiatrí́a y salud mental·Francisco AcostaBeatriz Cabrera
Jul 11, 2012·The International Journal of Pharmacy Practice·Stephen R CarterLesley White
Feb 28, 2014·Journal of the American Association of Nurse Practitioners·Kathy J WheelerMary B Neiheisel
Apr 21, 2019·Military Medicine·Debbie G A JanssenEibert R Heerdink
May 16, 2020·International Journal of Environmental Research and Public Health·Carles Vilaplana-CarnereroMaria Rubio-Valera
Feb 12, 2020·Biological Psychiatry : Cognitive Neuroscience and Neuroimaging·Ryan SmithMartin P Paulus

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