Patients prefer once-daily glaucoma drops.

Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie
Alex J BullerBrian L Hercules

Abstract

The relationship between complexity of eye drop regime and compliance is not straightforward, i.e. fewer drops may not mean better compliance. We investigated the level of inconvenience different eye drop regimes incurred in comparison with a once-daily (OD) regime for patients experienced with using topical anti-glaucoma medication. Patients indicated the level of inconvenience from drop regimes of 1, 2, 3 or 4 times daily on 10-cm visual analogue scales. The score for the OD regime was then compared with the scores for the other regimes using paired t-tests with Bonferroni correction. At a significance limit of p = 0.05, five of six subgroups indicated once-a-day drops were significantly more convenient than other regimes. Patients who had used the OD regime considered this difference greater than those who had not. This study's results offer some pragmatic guidance on choice of therapy and on counselling patients about compliance. We would suggest starting patients on OD drops in preference to alternatives to promote compliance.

References

Feb 15, 1987·American Journal of Ophthalmology·M A KassJ J Goldberg
May 1, 1993·American Journal of Public Health·J H GurwitzJ Avorn
Dec 16, 2000·Eye·A G KonstasC Sardelli

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Citations

Oct 24, 2007·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·John Cameron BuchanDavid Gilmour
Apr 17, 2014·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Gauti JóhannessonEinar Stefánsson
Sep 20, 2008·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Christine M G OlthoffJan S A G Schouten
Jul 23, 2020·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Thomas F FreddoNadine Furtado

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