Patients preferences for different corticosteroid vehicles are highly variable

The Journal of Dermatological Treatment
Kayla FelixSteven R Feldman

Abstract

Introduction: Topical corticosteroids, available in an array of vehicles are used to control a variety of inflammatory skin diseases. Patients preferences for different vehicles may affect their willingness to use treatment. We assess corticosteroid vehicle preference and potential impact of topical characteristics on adherence and quality of life in patients with psoriasis.Methods: Subjects with psoriasis were recruited from Wake Forest University Dermatology Clinic. Subjects sampled desoximetasone 0.25% spray, betamethasone valerate 0.1% cream, triamcinolone acetonide 0.1% ointment, fluocinonide 0.05% gel, betamethasone valerate 0.1% lotion, clobetasol propionate 0.05% foam, and fluocinonide 0.05% solution in a predetermined randomized order. Subjects completed a Vehicle Preference Measure, Determinants of Adherence Measure, and a Determinants of Quality of Life Measure.Results: Patients preferences for the various products were highly variable. Regarding Determinants of Adherence, patients perception of absorption of the medication was ranked as 'quite important/extremely important' by 85% of total subjects. A majority of patients rated medication side effects as 'quite important/extremely important' when asked to consider t...Continue Reading

References

Aug 14, 1998·Journal of the American Academy of Dermatology·D Piacquadio, A Kligman
Apr 12, 2003·American Journal of Clinical Dermatology·Steven R Feldman, Tamara S Housman
Oct 3, 2006·Journal of the American Academy of Dermatology·Katherine K BrownAlexa B Kimball
Jan 23, 2008·Journal of the American Academy of Dermatology·Emily J Fisher, Brian B Adams
Sep 1, 2011·Acta Dermato-venereologica·Ewa HrehorówJacek C Szepietowski
Feb 12, 2017·American Journal of Clinical Dermatology·Steven R FeldmanPeter van de Kerkhof

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Citations

Jun 5, 2021·Expert Opinion on Pharmacotherapy·Veronica K EmmerichSteven R Feldman

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