Patients' preferences for osteoporosis drug treatment: a discrete choice experiment

Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
Esther W de Bekker-GrobE W Steyerberg

Abstract

Active case finding for osteoporosis is used to identify patients at high fracture risk who may benefit from preventive drug treatment. We investigated the relative weight that women place on various aspects of preventive drugs in a discrete choice experiment. Our patients said they were prepared to take preventive drugs even if side effects were expected. Active case finding for osteoporosis is used to identify patients who may benefit from preventive drugs. We aimed to elicit the relative weight that patients place on various aspects of preventive drug treatment for osteoporosis. We designed a discrete choice experiment, in which women had to choose between drug profiles that differed in five treatment attributes: effectiveness, side effects (nausea), total treatment duration, route of drug administration, and out-of-pocket costs. We included 120 women aged 60 years and older, identified by osteoporosis case finding in 34 general practices in the Netherlands. A conditional logit regression model was used to analyse the relative importance of treatment attributes, the trade-offs that women were willing to make between attributes, and their willingness to pay. All treatment attributes proved to be important for women's choices....Continue Reading

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Citations

May 12, 2010·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·S L SilvermanD T Gold
Sep 15, 2010·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·J DarbàI Padró
Mar 22, 2013·Calcified Tissue International·Mickael HiligsmannJean-Yves Reginster
Apr 10, 2009·PharmacoEconomics·Esther W de Bekker-GrobEwout W Steyerberg
May 3, 2013·Applied Health Economics and Health Policy·A Brett HauberF Reed Johnson
Feb 1, 2014·Arthritis Research & Therapy·Mickaël HiligsmannAnnelies Boonen
Apr 27, 2013·PharmacoEconomics·Esther W de Bekker-Grob, Caspar G Chorus
Aug 27, 2014·Health Expectations : an International Journal of Public Participation in Health Care and Health Policy·Inger M JanssenFülöp Scheibler
Jun 24, 2010·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Tim H C DamenMarie-Louise Essink-Bot
Oct 5, 2010·Reproductive Biomedicine Online·N M van MelloP J Hajenius
Mar 3, 2015·The Patient·Esther W de Bekker-GrobElly A Stolk
Aug 20, 2015·Current Rheumatology Reports·Mickaël HiligsmannAnnelies Boonen
Feb 12, 2013·Journal of Psychosomatic Obstetrics and Gynaecology·Floortje VlemmixMarjolein Kok
Jun 26, 2013·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Ken DealPaul Moayyedi
Jan 8, 2013·Journal of Affective Disorders·Thomas M ZimmermannAnette Wolfrath
Jan 15, 2015·Diabetes Therapy : Research, Treatment and Education of Diabetes and Related Disorders·A Brett HauberLarry Radican
Sep 25, 2012·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Mi-Hai ParkEui-Kyung Lee
Jun 30, 2016·BioResearch Open Access·Justine TanjayaJin Hee Kwak
Oct 12, 2018·Tropical Medicine & International Health : TM & IH·Frederick G B GoddardMatthew C Freeman
Jun 10, 2020·International Journal of Environmental Research and Public Health·Erping JiaJuyang Xiong
Oct 26, 2018·International Journal of Health Care Quality Assurance·Mina BahrampourMohsen Barouni
Jul 3, 2020·Patient Preference and Adherence·Peita L Graham-ClarkeSandra Florez
Jul 17, 2020·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Daphne C VoormolenUNKNOWN CENTER-TBI participants and investigators
Sep 28, 2018·HSS Journal : the Musculoskeletal Journal of Hospital for Special Surgery·Benedict U NwachukwuTodd J Albert
Dec 31, 2019·Social Science & Medicine·E W de Bekker-GrobJ D Swait
Apr 23, 2021·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Louis S MatzaKristina S Boye

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