Patients' understanding of the reasons for starting and discontinuing inhaled corticosteroids.

British Journal of Clinical Pharmacology
Tanja T MenckebergJ A M Raaijmakers

Abstract

Although early discontinuation of treatment in new users of inhaled corticosteroids (ICS) has been widely discussed, the reasons for stopping have not been investigated in depth. We aimed to describe reasons for discontinuation from a patient's perspective in relation to their experience of symptoms at the time of the investigation. A cross-sectional study among new users that discontinued ICS use in the Netherlands was performed. Patients were interviewed by telephone, aiming to identify the symptoms for which they were prescribed ICS, the reasons for discontinuing treatment and the respiratory symptoms patients still experienced at the time of the survey. In addition, automated dispensing records of all patients were retrieved. From 287 eligible patients, 230 (80.1%) were interviewed. Only 22 patients (9.6%) mentioned asthma as the reason for a first ICS prescription. A decrease in symptoms was the main reason for discontinuation (45%). Thirty patients (13%) reported clinically significant residual symptoms. These patients reported more seasonal variation of symptoms and were more often prescribed short-acting beta(2)-agonists. The majority of patients mentioned a wide range of symptoms and conditions, other than asthma or ch...Continue Reading

References

Feb 1, 1994·American Journal of Respiratory and Critical Care Medicine·C S Rand, R A Wise
Nov 26, 1999·The European Respiratory Journal·E F JuniperD R King
Dec 22, 1999·Respiratory Medicine·G M CochraneP Chanez
May 4, 2001·The European Respiratory Journal·M D EisnerP D Blanc
Jan 5, 2002·Annals of Internal Medicine·Johanna L Keely, UNKNOWN American College of Physicians-American Society of Internal Medicine
Mar 29, 2002·The Annals of Pharmacotherapy·Theresa I ShiremanCharles J Moomaw
Sep 28, 2002·JAMA : the Journal of the American Medical Association·Morris WeinbergerWilliam M Tierney
May 9, 2003·Respiratory Medicine·T P van StaaS Suissa
Dec 12, 2003·European Journal of Cardiovascular Nursing : Journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology·Sabina De Geest, Eduardo Sabaté
Apr 29, 2004·The Annals of Pharmacotherapy·Nadia A Amruso, Michael L O'Neal
Jun 4, 2004·Quality & Safety in Health Care·N BarberR Horne
Aug 12, 2004·Respiratory Medicine·N S Breekveldt-PostmaR M C Herings
Feb 5, 2005·Respirology : Official Journal of the Asian Pacific Society of Respirology·UNKNOWN Asia Pacific COPD Roundtable Group
Oct 18, 2005·Respiratory Medicine·Elizabeth F JuniperUNKNOWN GOAL Committee
May 17, 2006·Primary Care Respiratory Journal : Journal of the General Practice Airways Group·John HaughneyJennifer Cleland
May 17, 2006·Primary Care Respiratory Journal : Journal of the General Practice Airways Group·Hilary PinnockAziz Sheikh
Jul 15, 2006·Chest·Richard S Irwin, Naomi D Richardson
Apr 24, 2007·Respiratory Medicine·Nicola J Roberts, Martyn R Partridge
Jan 24, 2008·Journal of Clinical Pharmacy and Therapeutics·H BuurmaA C G Egberts

❮ Previous
Next ❯

Citations

Dec 31, 2010·International Journal of Chronic Obstructive Pulmonary Disease·Suzanne C Lareau, Barbara P Yawn
Aug 17, 2010·Pharmacoepidemiology and Drug Safety·Ellen S KosterAnke-Hilse Maitland-van der Zee
Sep 29, 2011·Pharmacoepidemiology and Drug Safety·Ellen S KosterAnke-Hilse Maitland-van der Zee
Aug 25, 2015·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·David S HutchinsUNKNOWN IPSOR Medication Adherence and Persistence Special Interest Group
Aug 21, 2013·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·John E ZeberUNKNOWN ISPOR Medication Adherence Good Research Practices Working Group
Sep 24, 2010·Postgraduate Medicine·Len FromerBarbara Yawn
Jan 13, 2021·Pediatric Pulmonology·Lynn B OrriënsCristina Longo

❮ Previous
Next ❯

Related Concepts

Related Feeds

Adrenergic Receptors: Trafficking

Adrenergic receptor trafficking is an active physiological process where adrenergic receptors are relocated from one region of the cell to another or from one type of cell to another. Discover the latest research on adrenergic receptor trafficking here.