Pattern electroretinograms for the detection of neural loss in patients with permanent temporal visual field defect from chiasmal compression.

Documenta Ophthalmologica. Advances in Ophthalmology
Leonardo P CunhaMário L R Monteiro

Abstract

To evaluate the ability of full-field and hemifield pattern electroretinogram (PERG) parameters to differentiate between healthy eyes and eyes with band atrophy (BA) of the optic nerve. Twenty-six eyes from 26 consecutive patients with permanent temporal hemianopic visual field defects and BA of the optic nerve from previous chiasmal compression and 26 healthy subjects were studied prospectively. All patients were submitted to an ophthalmic examination including Humphrey 24-2 SITA Standard automated perimetry. Full-field and hemifield (nasal and temporal) stimulation transient pattern electroretinograms (PERG) were recorded using checkerboard screens. Amplitudes and peak times for the P50 and N95 as well as the overall P50+N95 amplitude were measured. The intraocular N95:P50 amplitude ratio was calculated. Comparisons were made using Student's t-test. Receiver operating characteristic (ROC) curves were used to describe the ability of PERG parameters to discriminate the groups. Full-field P50, N95, and P50+N95 amplitude values were significantly smaller in eyes with BA than in control eyes (P < 0.001). Nasal and temporal hemifield PERG studies revealed significant differences in N95 and P50+N95 amplitudes measurements. No signif...Continue Reading

Associated Clinical Trials

References

Jul 1, 1992·The British Journal of Ophthalmology·E O'DonaghueG Weinstein
Jan 1, 1990·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·T A Berninger, W Heider
Oct 1, 1989·Documenta Ophthalmologica. Advances in Ophthalmology·M Bach, A Speidel-Fiaux
Sep 1, 1988·Documenta Ophthalmologica. Advances in Ophthalmology·K HolopigianI Siegel
Nov 1, 1987·Documenta Ophthalmologica. Advances in Ophthalmology·M S MarxS M Podos
Mar 1, 1987·The British Journal of Ophthalmology·G E Holder
Jan 1, 1985·Experimental Brain Research·L MaffeiH Holländer
Apr 30, 1998·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·K RütherE Zrenner
Jan 1, 1997·Documenta Ophthalmologica. Advances in Ophthalmology·M BachJ Gerling
Sep 1, 2000·The British Journal of Ophthalmology·D N ParmarG E Holder
Dec 22, 2000·American Journal of Ophthalmology·J B KerrisonN J Newman
Apr 17, 2003·Current Opinion in Ophthalmology·Donald C Hood
Jun 19, 2004·The British Journal of Ophthalmology·M L R MonteiroM D Bronstein
Jan 5, 2005·Ophthalmology·Lori M VenturaRichard K Parrish
Jun 28, 2005·Investigative Ophthalmology & Visual Science·Donald C HoodRobert Ritch
Aug 29, 2006·Investigative Ophthalmology & Visual Science·Lori M VenturaVittorio Porciatti
Oct 27, 2006·Investigative Ophthalmology & Visual Science·Michael BachJens Funk
Apr 17, 2007·Documenta Ophthalmologica. Advances in Ophthalmology·Graham E HolderUNKNOWN International Society for Clinical Electrophysiology of Vision

❮ Previous
Next ❯

Citations

Oct 12, 2012·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Mário L R MonteiroMaria K Oyamada
Jul 31, 2013·Documenta Ophthalmologica. Advances in Ophthalmology·Kenzo HokazonoMário L R Monteiro
Jul 22, 2010·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Mário L R MonteiroLeonardo P Cunha
Jan 13, 2018·Journal of Glaucoma·André C KreuzMario L R Monteiro
Dec 3, 2015·International Ophthalmology Clinics·Rod Foroozan

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie
Mário L R MonteiroMaria K Oyamada
Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society
J M KhouryJ C Tsai
© 2022 Meta ULC. All rights reserved