PMID: 3753901Mar 14, 1986Paper

Pattern formation during vulval development in C. elegans

Cell
P W Sternberg, H R Horvitz

Abstract

Previous studies have shown that the development of the vulva of the C. elegans hermaphrodite involves six multipotential hypodermal cells as well as the gonadal anchor cell, which induces vulval formation. Our further examination of the interactions among these seven cells has led to the following model. Each hypodermal precursor cell becomes determined to adopt one of its three potential fates; each of these fates is to generate a particular cell lineage. In the absence of cellular interactions each precursor cell will generate the nonvulval cell lineage; an inductive signal from the anchor cell is required for a precursor cell to generate either of the two types of vulval cell lineages. The inductive signal is spatially graded, and the potency of the signal specifies which lineage is expressed by each of the tripotential precursor cells.

References

Aug 10, 1976·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·J E Sulston
Sep 1, 1979·Molecular & General Genetics : MGG·H R HorvitzR K Herman
Jan 20, 1978·Science·S A KauffmanK Trabert
Mar 1, 1977·Developmental Biology·J E Sulston, H R Horvitz
Apr 7, 1977·Journal of Theoretical Biology·J LewisL Wolpert
May 1, 1974·Genetics·S Brenner
Jan 1, 1971·Current Topics in Developmental Biology·L Wolpert
Jan 31, 1970·Nature·F Crick
Jan 1, 1984·Annual Review of Genetics·P W Sternberg, H R Horvitz
Sep 1, 1983·Cell·I S GreenwaldH R Horvitz
Nov 1, 1983·Developmental Biology·J E SulstonJ N Thomson
Mar 1, 1982·Proceedings of the National Academy of Sciences of the United States of America·J M Belote, B S Baker
Feb 1, 1981·Developmental Biology·J E Sulston, H R Horvitz
Aug 1, 1980·Developmental Biology·J E Sulston, J G White
Aug 1, 1980·Developmental Biology·J E SulstonJ N Thomson
Feb 14, 1970·Nature·E M Deuchar

❮ Previous
Next ❯

Citations

May 24, 2000·Developmental Dynamics : an Official Publication of the American Association of Anatomists·G Shemer, B Podbilewicz
Aug 1, 1992·Developmental Dynamics : an Official Publication of the American Association of Anatomists·J C WayA Y Wang
Dec 1, 1994·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·J C WayM S Hung
Jun 1, 1996·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·M Sundaram, M Han
Nov 1, 1988·Developmental Biology·P W Sternberg, H R Horvitz
Apr 1, 1989·Developmental Biology·H Nishida, N Satoh
Jun 1, 1988·Trends in Neurosciences·P W Sternberg
Mar 22, 2003·Experimental Cell Research·Nadeem Moghal, Paul W Sternberg
Mar 22, 2003·Experimental Cell Research·Raymond C HarrisRobert J Coffey
May 14, 1999·Trends in Genetics : TIG·A EizingerR J Sommer
Nov 6, 2002·Biochimica Et Biophysica Acta·Dorota A Bulik, Phillips W Robbins
Oct 17, 2001·Gene·G MichauxM Labouesse
Aug 1, 1997·Current Opinion in Genetics & Development·P W Sternberg, M A Félix
Sep 20, 2005·Nature·Alejandro Colman-LernerRoger Brent
Sep 29, 2012·Proceedings of the National Academy of Sciences of the United States of America·Kah Yee GohTakao Inoue
Mar 22, 2012·Proceedings of the National Academy of Sciences of the United States of America·Francis Corson, Eric Dean Siggia
Sep 3, 1996·Proceedings of the National Academy of Sciences of the United States of America·A P Newman, P W Sternberg
Apr 1, 1994·Molecular Biology of the Cell·L S HuangP W Sternberg
May 1, 1997·Molecular Biology of the Cell·G M Lesa, P W Sternberg
Jan 1, 2010·BMC Developmental Biology·Adeline Seah, Paul W Sternberg
Jan 7, 2005·BMC Evolutionary Biology·Scott Everet BairdJustin C Bohrer
Jun 9, 2006·BMC Genetics·Aidyl S Gonzalez-Serricchio, Paul W Sternberg
Jul 14, 2005·BMC Neuroscience·Michael Y ChaoAnne C Hart
May 22, 2007·PLoS Computational Biology·Jasmin FisherThomas A Henzinger
Mar 20, 2010·PLoS Genetics·Christian BraendleMarie-Anne Félix
Nov 19, 2013·PLoS Genetics·Alejandro Vasquez-RifoMartin J Simard

❮ Previous
Next ❯

Related Concepts

Related Feeds

Blood And Marrow Transplantation

The use of hematopoietic stem cell transplantation or blood and marrow transplantation (bmt) is on the increase worldwide. BMT is used to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. Here is the latest research on bone and marrow transplantation.

Cell eTOC

Cell is a scientific journal publishing research across a broad range of disciplines within the life sciences field. Discover the latest research from Cell here.

Adhesion Molecules in Health and Disease

Cell adhesion molecules are a subset of cell adhesion proteins located on the cell surface involved in binding with other cells or with the extracellular matrix in the process called cell adhesion. In essence, cell adhesion molecules help cells stick to each other and to their surroundings. Cell adhesion is a crucial component in maintaining tissue structure and function. Discover the latest research on adhesion molecule and their role in health and disease here.