PMID: 8953667Jan 1, 1996Paper

Pattern of HIV viraemia and CD4 levels in relation to pregnancy in HIV-1 infected women

Scandinavian Journal of Infectious Diseases
S LindgrenA Ehrnst

Abstract

The objective was to study HIV-1 viraemia and CD4 levels during and 6 months after pregnancy. HIV cultures on peripheral blood mononuclear cells (PBMC) and plasma from 225 samples were performed in 90 HIV-1 infected women with 59 continued and 35 terminated pregnancies. P-24 antigen and HIV-DNA were also studied. 34 women originated from European, 44 from African and 10 from other countries while 2 were of unknown origin. HIV was detected in 30% of the plasma cultures from the first trimester and in approximately 50% thereafter. Repeated plasma isolations did not give an indication of HIV activation, nor did the cross-sectional time-to-culture positivity in plasma and in PBMC, PBMC isolation frequencies, HIV-DNA and CD4 levels. The plasma viraemia frequencies were generally higher and the CD4 levels lower in the African women than in the European ones. Six months after delivery there was a significant decrease in the CD4 cell counts compared to delivery, but not when compared to the values during the first or second trimesters. The results showed that HIV activity during pregnancy was relatively stable, followed by indications of resumed activity during the first 6 months after delivery.

References

Aug 1, 1990·Journal of Clinical Microbiology·M M ReddyM H Grieco
Dec 14, 1989·The New England Journal of Medicine·R W CoombsL Corey
Dec 14, 1989·The New England Journal of Medicine·D D HoM Alam
Nov 1, 1989·American Journal of Obstetrics and Gynecology·R J BiggarJ J Goedert
Nov 1, 1988·European Journal of Haematology·B BöttigerG Biberfeld
Mar 3, 1989·JAMA : the Journal of the American Medical Association·P A SelwynM F Rogers
Aug 1, 1988·Clinical Immunology and Immunopathology·D DegenneP Bardos
Sep 1, 1988·Journal of Medical Virology·A EhrnstO Strannegård
Jan 18, 1985·JAMA : the Journal of the American Medical Association·G B ScottW P Parks
Nov 1, 1984·Reviews of Infectious Diseases·E D Weinberg
Aug 5, 1982·The New England Journal of Medicine·V SridamaL J DeGroot
Jul 1, 1994·Journal of Clinical Microbiology·I Van KerckhovenG van der Groen
Aug 16, 1994·Proceedings of the National Academy of Sciences of the United States of America·B WeiserH Burger
Jun 1, 1994·Obstetrics and Gynecology·F D JohnstoneJ Whitelaw
Dec 4, 1993·BMJ : British Medical Journal·S LindgrenM Böttiger
Nov 1, 1995·British Journal of Obstetrics and Gynaecology·C ThorneC Peckham
Oct 1, 1995·AIDS Research and Human Retroviruses·L ErcoliC Tomino
Mar 20, 1996·AIDS Research and Human Retroviruses·J E ClementsM C Zink

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Citations

Oct 22, 2008·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Deven PatelMario Cortina-Borja
Jan 17, 2002·Acta Microbiologica Et Immunologica Hungarica·C Casper, E M Fenyö

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