Pattern of intracortical potential distribution during focal interictal epileptiform discharges (FIED) and its relation to spinal field potentials in the rat

Electroencephalography and Clinical Neurophysiology
C E ElgerH Caspers

Abstract

The pattern of intracortical potential distribution during focal interictal epileptiform discharges (FIED) was analysed with respect to the occurrence of descending neuronal activity to the spinal cord recorded as spinal field potentials (SFPs). The experiments were performed in rats. Epileptiform activity was elicited by application of penicillin to the motor cortex. The spread of active penicillin was limited by penicillinase in part of the experiments. (1) When penicillinase was applied 10--20 sec before penicillin to the cortical surface typical FIED appeared in the epicortical lead. During well-established focal activity they were accompanied by negative field potentials at a depth of 300 micrometers and 600 micrometers and by positive field potentials in deeper records. This pattern of intracortical potential distribution was not associated with characteristic SFPs. (2) When penicillinase was applied simultaneously with penicillin, the fully developed epicortical FIED were accompanied by negative intracortical field potentials which in this case reached a depth of 900 micrometers. In the layers below predominantly positive potential fluctuations occurred. This pattern of intracortical potential distribution was associated...Continue Reading

References

Mar 1, 1977·Electroencephalography and Clinical Neurophysiology·O ProhaskaH Petsche
Nov 1, 1979·Electroencephalography and Clinical Neurophysiology·I B Müller-PaschingerH Petsche
Jan 1, 1978·Annual Review of Neuroscience·D A Prince
Apr 1, 1970·Electroencephalography and Clinical Neurophysiology·R J GumnitC Vasconetto
Feb 1, 1967·Archives of Neurology·D A Prince, B J Wilder
Apr 1, 1980·Electroencephalography and Clinical Neurophysiology·C E Elger, E J Speckmann

❮ Previous
Next ❯

Citations

May 19, 1998·Annals of Neurology·T MimaH Shibasaki
May 1, 1982·Electroencephalography and Clinical Neurophysiology·C Silva-ComteC Ménini
Dec 1, 1983·Electroencephalography and Clinical Neurophysiology·C E Elger, E J Speckmann
Dec 1, 1983·Electroencephalography and Clinical Neurophysiology·E J SpeckmannA Lehmenkuehler
Oct 1, 1985·Electroencephalography and Clinical Neurophysiology·J WaldenO W Witte
Jan 1, 1987·Electroencephalography and Clinical Neurophysiology·O W WitteJ Walden
Nov 6, 1998·Electroencephalography and Clinical Neurophysiology·C A TassinariH Shibasaki
Jul 1, 1997·Epilepsia·H DooseB Neubauer
Mar 3, 2012·Journal of Neurosurgery. Pediatrics·Yanfang Shi, Huancong Zuo
Apr 12, 2003·Brain & Development·Katsuhiko OguroHiroatsu Hojo
Jan 12, 2013·Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række·John A Wilson, Helge J Nordal
Dec 22, 2004·Epilepsia·Hirokazu Oguni
Apr 30, 1984·Brain Research·J S Ebersole, A B Chatt
Feb 1, 1986·IEEE Transactions on Bio-medical Engineering·O J ProhaskaH Dragaun
Jul 14, 2012·Seizure : the Journal of the British Epilepsy Association·Stjepana Kovac, Beate Diehl
Sep 29, 2009·Clinical EEG and Neuroscience·Ali Gorji, Erwin-Josef Speckmann

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.