Pattern of Lymphatic Spread of Esophageal Cancer at the Cervicothoracic Junction Based on the Tumor Location : Surgical Treatment of Esophageal Squamous Cell Carcinoma of the Cervicothoracic Junction

Annals of Surgical Oncology
Makoto YamasakiYuichiro Doki

Abstract

There is no consensus about the extent of lymphadenectomy for patients with esophageal squamous cell carcinoma at the cervicothoracic junction (CT-ESCC). The purpose of this study was to examine the pattern of lymph node spread in patients with CT-ESCC and the extent of lymphadenectomy that is necessary. We included 64 consecutive patients with CT-ESCC who underwent surgery. All patients were divided into two groups based on the location of the epicenter or anal edge of the primary tumor. Using the height of the epicenter, 27 and 37 patients were classified as having cervical-centered and thoracic-centered tumors, respectively; while, using the height of the anal edge, 38 and 26 patients had tumors that were cervical-localized and thoracic-invading, respectively. In the patients with cervical-centered tumors, the incidences of metastasis and/or recurrences in the cervical paraesophageal, supraclavicular, and upper mediastinal nodes were 21.4-28.5 %. No patient had metastasis or recurrence in the middle and lower mediastinal and perigastric nodes. In patients with thoracic-centered tumors, the lymph node metastasis and/or recurrence spread to the cervical paraesophageal (41.7 %), supraclavicular (25 %), and upper mediastinal (55...Continue Reading

References

Mar 21, 2006·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Trevor LeongRodney J Hicks
Jan 26, 2007·Scandinavian Journal of Surgery : SJS : Official Organ for the Finnish Surgical Society and the Scandinavian Surgical Society·J R SiewertM Feith
May 12, 2007·The Annals of Otology, Rhinology, and Laryngology·Shigeru HiranoShin-ichi Takagita
Jan 22, 2009·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Hideaki ShimadaHisahiro Matsubara
Nov 27, 2009·Annals of Surgical Oncology·Makoto YamasakiYuichiro Doki
Feb 8, 2011·CA: a Cancer Journal for Clinicians·Ahmedin JemalDavid Forman
Jun 28, 2011·The Annals of Thoracic Surgery·Hee-Jin JangJae Ill Zo
May 15, 2012·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Masahiro YanagawaJun Hatazawa
Dec 12, 2012·World Journal of Surgery·Hiroshi MiyataYuichiro Doki

❮ Previous
Next ❯

Citations

Feb 15, 2020·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·Makoto YamasakiYuichiro Doki
Sep 5, 2021·Annals of Surgical Oncology·Yoshihisa NumataYasuhiro Shimizu

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Squamous Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.