Pattern of nodal metastasis for primary and reoperative thyroid cancer

World Journal of Surgery
Andreas MachensHenning Dralle

Abstract

This retrospective investigation was undertaken to clarify the pattern of nodal metastasis in papillary (PTC) and medullary (MTC) thyroid carcinoma. Nodal metastases are associated with recurrence of both PTCs and MTCs. The extent of lymph node dissection is controversial owing to the lack of reliable diagnostic criteria for nodal metastases other than histopathology. Between November 1994 and October 1999 a total of 296 patients (134 PTCs, 162 MTCs) underwent total thyroidectomy in conjunction with a standard resection of at least the cervicocentral lymph node compartment. Of 10,446 sampled lymph nodes, 1641 were positive. All nodes were related to their respective cervicomediastinal compartments. The ipsilateral cervicolateral compartment was involved almost as often as the cervicocentral compartment in primary PTC (29% vs. 32%), reoperative PTC (21% vs. 37%), primary MTC (34% vs. 34%), and reoperative MTC (49% vs. 65%). The contralateral cervicolateral and mediastinal compartments were more rarely affected, and were least affected in the primary setting. From these data was derived an individualized surgical strategy for PTC and MTC. This concept rests on the joint resection of cervicocentral and ipsilateral cervicolateral c...Continue Reading

Citations

Mar 2, 2005·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·H VogelsangJ R Siewert
Feb 27, 2007·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·O Gimm, H Dralle
Sep 1, 2005·Langenbeck's Archives of Surgery·G ArditoA M Farinon
Jul 16, 2008·Langenbeck's Archives of Surgery·Isabella Merante BoschinMariaRosa Pelizzo
Mar 5, 2013·Langenbeck's Archives of Surgery·Henning DralleUNKNOWN German Societies of General and Visceral Surgery; Endocrinology; Nuclear Medicine; Pathology; Radiooncology; Oncological Hem
Jun 22, 2005·Current Treatment Options in Oncology·Nadine R Caron, Orlo H Clark
May 24, 2005·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·A Machens, H Dralle
Oct 3, 2002·Surgical Oncology·Sam M WisemanNestor R Rigual
Jan 20, 2006·Thyroid : Official Journal of the American Thyroid Association·David S CooperUNKNOWN American Thyroid Association Guidelines Taskforce
May 28, 2009·Thyroid : Official Journal of the American Thyroid Association·UNKNOWN American Thyroid Association Guidelines Task ForceSamuel A Wells
Oct 29, 2009·Thyroid : Official Journal of the American Thyroid Association·UNKNOWN American Thyroid Association (ATA) Guidelines Taskforce on Thyroid Nodules and Differentiated Thyroid CancerR Michael Tuttle
Jun 9, 2009·Thyroid : Official Journal of the American Thyroid Association·Douglas W Ball
Jul 9, 2009·Thyroid : Official Journal of the American Thyroid Association·Ernest L MazzaferriDavid L Steward
Dec 17, 2009·Thyroid : Official Journal of the American Thyroid Association·Jennifer A Sipos
Jul 26, 2012·Thyroid : Official Journal of the American Thyroid Association·Davide GiordanoVerter Barbieri
Oct 20, 2012·Current Opinion in Oncology·Henning Dralle, Andreas Machens
Oct 6, 2006·Nuclear Medicine Communications·Domenico Rubello, Michael J O'Doherty
Jan 22, 2011·Current Opinion in Otolaryngology & Head and Neck Surgery·N Gopalakrishna Iyer, Ashok R Shaha
Sep 9, 2008·Ultrasound Quarterly·Sheila Sheth, Ulrike M Hamper
Apr 9, 2008·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Ann D King
Dec 21, 2004·Journal of Internal Medicine·A MachensH Dralle
Nov 5, 2008·Annals of Surgical Oncology·Andreas Machens, Henning Dralle
Feb 11, 2010·Annals of Surgical Oncology·Bon Seok KooYoung Chang Lim
Jul 3, 2010·Annals of Surgical Oncology·Tarek ZetouneRasa Zarnegar
Nov 19, 2011·Annals of Surgical Oncology·Soo Youn BaeJee Soo Kim
Aug 16, 2008·Endocrine Journal·Yasuhiro Ito, Akira Miyauchi
Jun 8, 2004·Acta chirurgica Iugoslavica·A DiklicV Bozic
Dec 7, 2013·Langenbeck's Archives of Surgery·T J Musholt

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