Pattern of ongoing discharge of single renal sympathetic neurons in the rabbit

Archives of Physiology and Biochemistry
K LupaA Niechaj

Abstract

Ongoing discharge in single renal sympathetic neurons was first studied in vagotomized rabbits without baroreceptor information (60 min after section of the aortic nerves). Under urethane + chloralose anaesthesia interspike-interval histograms were compiled and discharge rates were measured in 79 neurons. The following parameters were analysed: (a) the shortest, (b) the preferred and (c) the longest interspike-intervals, (d) discharge rate, (e) spread of a histogram, (f) coefficient of symmetry, and (g) coefficient of variability. The type of distribution of histograms and 9 correlations between some parameters were also assessed. These parameters were considered to make up the pattern of the ongoing discharge. The shortest, preferred and longest interspike-intervals of the ongoing discharge were: 14.1 +/- 0.9, 30.4 +/- 3.5 and 1672 +/- 82 ms. The mean rate of discharge amounted to 1.78 +/- 0.08 spikes/s. Three out of 9 correlation coefficients between the above parameters were statistically significant. In a second part, the effect of section of the aortic nerves and of 4-aminopyridine (a drug known to enhance synaptic transmission) on the pattern of ongoing discharge were also studied. Ten minutes after section of the aortic ...Continue Reading

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Citations

Jul 12, 2005·Autonomic Neuroscience : Basic & Clinical·K LupaA Niechaj

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