Pattern of rectal cancer recurrence after curative surgery

International Journal of Colorectal Disease
Minna RäsänenAnna Lepistö

Abstract

After curative rectal cancer surgery, local recurrences manifest in 2.4-10% and distant metastases in 20-50% of patients. The effectiveness of different surveillance regimens is not well established. We evaluated the pattern of recurrence and the utility of different surveillance instruments. Risk factors for recurrence were also recorded. This retrospective study comprises 580 consecutive rectal cancer patients operated on at Helsinki University Central Hospital, Finland, during 2005-2011. Data were collected from patient records. After exclusions, 481 patients treated with curative intent remained. Patients were followed up according to an intensive surveillance program. Rectal cancer recurrence was observed in 124 patients (25.8%). Local recurrence manifested in 40 patients (8.3%) and distant metastases in 112 patients (23.3%). Recurrences were observed a median of 1.3 years after surgery. Twelve patients had to be followed up to find one local recurrence and four patients to find one distant metastasis. Recurrences detected during regular follow-up visits were discovered on average earlier than those detected in additional visits arranged because of patient symptoms (p = 0.023 for local recurrence, p = 0.001 for distant met...Continue Reading

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Citations

Sep 10, 2016·The Australian & New Zealand Journal of Obstetrics & Gynaecology·E Sun PaikDuk-Soo Bae
Sep 14, 2016·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·M RäsänenA Lepistö
May 4, 2018·Diseases of the Colon and Rectum·Nitin Mishra
Nov 10, 2018·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·T LehtonenA Lepistö
Apr 7, 2019·Abdominal Radiology·Dhakshinamoorthy GaneshanCourtney C Moreno

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