Pattern of Tumour Spread of Common Primary Tumours as Seen on Magnetic Resonance Imaging

Pathology Oncology Research : POR
David Laszlo TarnokiDirk Pickuth

Abstract

Although some reports with computed tomography and bone scintigraphy are available in the literature, the distinct epidemiologic description of skeletal metastatic pattern of various tumors is still lacking. This study uses a novel approach to identify skeletal metastases from magnetic resonance imaging (MRI) data to describe metastatic pattern in common malignancies. A retrospective analysis of 130 cancer patients (42 lung, 56 breast, 11 prostate cancers; 21 multiple myeloma) with vertebral metastases and without disseminated disease, and whom underwent a whole body 3Tesla MRI investigation (Discovery MR750w), was carried out. Multiple myeloma had the most commonly disseminated metastatic disease (95%) compared to lung (28%), breast (44%) and prostate (71%) cancers. Lung cancer was related to more frequent pedicle involvement compared to breast or prostate cancer (29, 9 and 0%, p < 0.05). Pathologic fracture was mainly associated with multiple myeloma (43%). The prevalence of lung cancer metastases was more frequent in the lumbal spine (81%), as well as particular in C7, D7, D8, D9 and L1, compared to breast cancers. Most differences among tumors were detected in the extravertebral osseous metastatic pattern (p < 0.05). The hi...Continue Reading

References

Jun 1, 1992·AJR. American Journal of Roentgenology·P R AlgraB Van Kooten
Jan 1, 1992·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·N J BundredJ G Ratcliffe
Feb 1, 1987·RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin·F WeigertK Pfändner
Sep 1, 1988·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·J B SørensenP Dombernowsky
Jan 1, 1987·British Journal of Cancer·R E Coleman, R D Rubens
Jan 1, 1985·Spine·J Schaberg, B J Gainor
Jun 1, 1995·Cancer·S J FabozziA M el-Mahdi
Nov 15, 1997·Cancer·R E Coleman
Mar 31, 1999·International Journal of Radiation Oncology, Biology, Physics·F J LagerwaardP I Schmitz
Jun 3, 2000·Human Pathology·L BubendorfM J Mihatsch
Mar 30, 2004·The Oncologist·Paul Klimo, Meic H Schmidt
Nov 6, 2004·Journal of Neuro-oncology·Narayan SundaresanRobert Holtzman
Mar 5, 2005·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·L Joseph MeltonS Vincent Rajkumar
Aug 26, 2006·Nature Clinical Practice. Neurology·Timothy F WithamZiya L Gokaslan
Oct 13, 2006·The Journal of the American Academy of Orthopaedic Surgeons·Andrew P WhiteJonathan N Grauer
Oct 26, 2006·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Robert E Coleman
Dec 23, 2006·Surgical Oncology·Daniel M Sciubba, Ziya L Gokaslan
Jan 16, 2008·Clinical Orthopaedics and Related Research·Hideshi SugiuraTetsuya Mitsudomi
Jun 7, 2008·Expert Review of Anticancer Therapy·German A MarulandaNazanin Khakpour
Apr 1, 1948·The British Journal of Surgery·R SHACKMAN, C V HARRISON
Jul 3, 2010·Journal of Neurosurgery. Spine·Daniel M SciubbaZiya L Gokaslan
Nov 18, 2011·Cancer Metastasis Reviews·Davina Cossigny, Gerald M Y Quan
Mar 23, 2012·Asian Spine Journal·Chong-Suh Lee, Chul-Hee Jung
Sep 20, 2012·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Susan L GreenspanNeil M Resnick
Sep 27, 2013·Nuclear Medicine Review. Central & Eastern Europe·Vahid Reza Dabbagh KakhkiMaryam Torabian-Kakhki
Dec 20, 2013·Lancet·Paolo Vineis, Christopher P Wild
Aug 19, 2014·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·M RiihimäkiK Hemminki
Dec 17, 2014·Radiation Oncology·Antonio José Conde MorenoMaría Albert Antequera
Dec 30, 2014·Cancer Research and Treatment : Official Journal of Korean Cancer Association·Ik-Chan SongDeog-Yeon Jo

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