Pattern, time of birth, and morphogenesis of sensillum progenitors in Drosophila

Microscopy Research and Technique
A Younossi-Hartenstein, V Hartenstein

Abstract

In this paper we describe the spatiotemporal pattern of sensillum progenitors (SOPs), as well as the way in which these cells segregate from the ectoderm and proliferate. The birthdate of SOPs was determined by applying short heat pulses to embryos carrying the Nintra construct [Struhl et al. (1993), Cell, 74:331-345] which allows the overexpression of the active Notch protein at defined developmental stages and thereby eliminates SOPs which would normally segregate during these stages. Our results show that sensillum progenitors appear in several waves which to some degree respect sensillum modality, as well as dorsoventral sensillum location. The four early SOPs (stage 10) give rise exclusively to multiply innervated sensilla, chordotonal organs, and some multidendritic neurons. The second wave (early stage 11) produces the remaining chordotonal organs, some multidendritic neurons, and the dorsal singly innervated mechanosensilla. The third wave (late stage 11), in a dorsal-to-ventral succession, gives rise to the lateral and ventral singly innervated hair and papilla sensilla. Labeling developing SOPs with specific markers demonstrates that only progenitors of subepidermally located chordotonal organs and multidendritic neur...Continue Reading

References

Nov 1, 1990·Developmental Biology·V Hartenstein, J W Posakony
Jan 23, 1998·Microscopy Research and Technique·P Green, V Hartenstein
Mar 1, 1937·Proceedings of the National Academy of Sciences of the United States of America·D F Poulson
Feb 1, 1987·Roux's Archives of Developmental Biology : the Official Organ of the EDBO·Rolf Bodmer, Yuh Nung Jan
Jul 1, 1981·Wilhelm Roux's Archives of Developmental Biology·Ruth LehmannJ A Campos-Ortega
May 1, 1986·Roux's Archives of Developmental Biology : the Official Organ of the EDBO·Volker Hartenstein, Jose A Campos-Ortega
Jul 1, 1986·Roux's Archives of Developmental Biology : the Official Organ of the EDBO·Alain GhysenYuh -Nung Jan

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Citations

Feb 16, 2007·Gene Expression Patterns : GEP·Simon G SprecherVolker Hartenstein
Sep 10, 2013·Wiley Interdisciplinary Reviews. Developmental Biology·Volker Hartenstein, Andreas Wodarz
Aug 7, 2004·Current Biology : CB·Rachel Kraut, Kai Zinn
Jan 23, 1998·Microscopy Research and Technique·P Green, V Hartenstein

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