Patterning droplets with durotaxis

Proceedings of the National Academy of Sciences of the United States of America
Robert W StyleEric R Dufresne

Abstract

Numerous cell types have shown a remarkable ability to detect and move along gradients in stiffness of an underlying substrate--a process known as durotaxis. The mechanisms underlying durotaxis are still unresolved, but generally believed to involve active sensing and locomotion. Here, we show that simple liquid droplets also undergo durotaxis. By modulating substrate stiffness, we obtain fine control of droplet position on soft, flat substrates. Unlike other control mechanisms, droplet durotaxis works without imposing chemical, thermal, electrical, or topographical gradients. We show that droplet durotaxis can be used to create large-scale droplet patterns and is potentially useful for many applications, such as microfluidics, thermal control, and microfabrication.

References

Dec 1, 1996·Journal of Colloid and Interface Science·C W Extrand, Y Kumagai
Jun 27, 2000·Biophysical Journal·C M LoY L Wang
Jun 24, 2003·Nature Materials·Aurélie Lafuma, David Quéré
Nov 19, 2005·Science·Dennis E DischerYu-Li Wang
Jun 28, 2006·Langmuir : the ACS Journal of Surfaces and Colloids·Ashutosh ShastryKarl F Böhringer
Aug 19, 2007·Nature Materials·Laurent CourbinHoward A Stone
Jun 12, 1992·Science·M K Chaudhury, G M Whitesides
Aug 30, 2008·Langmuir : the ACS Journal of Surfaces and Colloids·Ramón Pericet-CámaraElmar Bonaccurso
Nov 20, 2009·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Byung Mook WeonJong Hoon Hahn
Nov 26, 2009·Langmuir : the ACS Journal of Surfaces and Colloids·Mordechai SokulerHans-Jürgen Butt
Jan 15, 2011·Physical Review Letters·Serge MoraYves Pomeau
Mar 17, 2011·Journal of Physics. Condensed Matter : an Institute of Physics Journal·B Roman, J Bico
Jun 4, 2011·Physical Review Letters·Elizabeth R JerisonEric R Dufresne
Jul 30, 2011·Physical Review Letters·B M WeonW-K Lee
Jan 10, 2012·The European Physical Journal. E, Soft Matter·S HaradaK Sato
Apr 3, 2012·Physical Review Letters·Antonin MarchandBruno Andreotti
Apr 18, 2012·Proceedings of the National Academy of Sciences of the United States of America·Léa TrichetBenoît Ladoux

❮ Previous
Next ❯

Citations

Nov 28, 2013·Analytical Chemistry·Christopher T CulbertsonMelissa Pressnall
Nov 10, 2013·Nature Communications·Robert W StyleEric R Dufresne
Jul 23, 2013·Proceedings of the National Academy of Sciences of the United States of America·Todd M Squires
Mar 22, 2014·Soft Matter·Andong He, John S Wettlaufer
Mar 22, 2014·Soft Matter·B B J StapelbroekA Eddi
Oct 7, 2015·Frontiers in Cellular Neuroscience·Lars BollmannKristian Franze
Apr 9, 2015·Biomechanics and Modeling in Mechanobiology·Houfu Fan, Shaofan Li
Feb 22, 2014·Journal of the Mechanical Behavior of Biomedical Materials·Pen-hsiu Grace ChaoWei-Ren Chang
Aug 5, 2015·Nature Communications·S KarpitschkaJ H Snoeijer
May 6, 2014·Current Biology : CB·Chiara GabellaAlexander B Verkhovsky
Jun 15, 2016·Proceedings of the National Academy of Sciences of the United States of America·Stefan KarpitschkaJacco H Snoeijer
Jun 28, 2016·Proceedings of the National Academy of Sciences of the United States of America·Anand Jagota
Jul 7, 2016·Proceedings of the National Academy of Sciences of the United States of America·Dayong ChenRobert E Cohen
Dec 21, 2016·Langmuir : the ACS Journal of Surfaces and Colloids·Tianshu LiuChung-Yuen Hui
Apr 28, 2017·Langmuir : the ACS Journal of Surfaces and Colloids·Tianshu LiuAnand Jagota
Apr 22, 2017·Soft Matter·Jian Hui GuanGary George Wells
Dec 10, 2016·Soft Matter·Haoyuan JingSiddhartha Das
Jan 13, 2017·Soft Matter·Francesco Mancarella, John S Wettlaufer
Dec 17, 2014·Soft Matter·Robert W StyleEric R Dufresne
Aug 14, 2015·Soft Matter·Robert W StyleEric R Dufresne
Jun 30, 2015·Soft Matter·Sabrina HaefnerKarin Jacobs
Jul 3, 2017·The Journal of Chemical Physics·Panagiotis E TheodorakisAndrey Milchev
Feb 13, 2018·Proceedings of the National Academy of Sciences of the United States of America·Menghua ZhaoMatthieu Roché
Apr 24, 2018·Soft Matter·Rafael D SchulmanKari Dalnoki-Veress
Jun 14, 2016·Chemical Society Reviews·Sławomir LachBartosz A Grzybowski
Jul 11, 2014·Nature Communications·Su Ji ParkJung Ho Je
Nov 15, 2017·Soft Matter·Menghua ZhaoJulien Dervaux
May 29, 2018·Soft Matter·Robert W Style, Qin Xu
Jan 31, 2019·Advanced Materials·Jing LiZuankai Wang
Feb 14, 2019·Soft Matter·Jiaqian LiZuankai Wang
Apr 16, 2019·Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences·J S Wettlaufer
Apr 18, 2014·Soft Matter·Robert W StyleEric R Dufresne
Feb 1, 2018·Soft Matter·Qin XuEric R Dufresne
Nov 19, 2019·Soft Matter·Shih-Yuan ChenKaren E Daniels
Dec 18, 2019·Soft Matter·Bhaskarjyoti SarmaDipankar N Basu
Dec 25, 2019·Nanoscale·Jiantao LengTienchong Chang
Jan 31, 2020·Soft Matter·Jakub KołaczQi-Huo Wei
Jan 24, 2015·Physical Review Letters·Tienchong ChangHuajian Gao
Aug 18, 2020·Soft Matter·Vasileios Charitatos, Satish Kumar
Nov 28, 2015·Physical Review Letters·Rafael D Schulman, Kari Dalnoki-Veress
Jul 27, 2017·The European Physical Journal. E, Soft Matter·Adam FortaisKari Dalnoki-Veress
Sep 17, 2017·Nature Communications·Qin XuEric R Dufresne
Jan 30, 2018·Physical Review Letters·Dan DanielJoanna Aizenberg
Feb 2, 2018·Soft Matter·Jesus BuenoHector Gomez
Jan 14, 2017·Physical Review. E·Longquan ChenHaibo Zhang
Jun 18, 2017·Physical Review. E·Chen Xuan, John Biggins

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.