Patterns and frequency of recurrences of squamous cell carcinoma of the vulva

Gynecologic Oncology
Jorien M WoolderinkMarian J E Mourits

Abstract

To analyze patterns and frequency of recurrences of squamous cell carcinoma (SCC) of the vulva after wide local excision (WLE) and superficial inguinal lymphadenectomy with separate incisions and to identify prognostic factors for the development of recurrences. Between January 1985 and December 1999, all 125 consecutive patients with primary SCC of the vulva, treated with WLE and superficial inguinal lymphadenectomy, were retrospectively analyzed. Recurrences were registered by localization as: local, skin bridge, groin or distant. A local recurrence was diagnosed in 29 (23%) patients, 11 (9%) developed a groin and 4 (3%) a distant recurrence. No skin bridge recurrences were identified. The 5 years local relapse-free survival was 70%. After a first local recurrence, 72% of these patients developed a second local recurrence. Adjusted for other predictors, older age (>74 years) is an independent risk factor for local recurrences (HR: 2.38; 95%-C.I.: 1.08-5.23) and stage III/IV cancer for developing groin/distant recurrences (HR: 3.03; 95%-C.I.: 1.0-9.18). WLE and superficial inguinal lymphadenectomy with separate incisions result in a high groin recurrence rate in this study; superficial lymphadenectomy should be replaced by dee...Continue Reading

References

Jul 1, 1986·Gynecologic Oncology·D S ShimmS A Aristizabal
Feb 1, 1993·Gynecologic Oncology·B PiuraJ Monaghan
Apr 1, 1996·British Journal of Obstetrics and Gynaecology·D Cavanagh, M S Hoffman
Aug 12, 1999·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·A S Truswell
Mar 10, 2001·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·P. G. Rose
Jan 1, 1993·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·R.N. GrimshawJ.M. Monaghan
Nov 19, 2002·Cancer·Joanne A De HulluAte G J Van Der Zee
Dec 7, 2002·Obstetrics and Gynecology·Roman RouzierBernard Jean Paniel
Sep 6, 2003·International Journal of Radiation Oncology, Biology, Physics·Angela KatzCharles F Levenback
Dec 12, 2003·Cancer·Maaike H M OonkAte G J van der Zee
Feb 8, 2005·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·M ArvasD Kösebay
Jun 25, 2005·Gynecologic Oncology·Tyler O KirbyJ Michael Straughn

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Citations

May 15, 2009·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Nicholas J Golda, Ronald G Wheeland
Feb 21, 2007·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·P M VogtK H Busch
Feb 15, 2008·Archives of Gynecology and Obstetrics·Gabriella FerrandinaGiovanni Scambia
Dec 25, 2012·Archives of Gynecology and Obstetrics·Jacek J SznurkowskiJanusz Emerich
Jun 29, 2012·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Jing LiZhong-qiu Lin
Dec 19, 2015·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Rosa M AlvarezArjun R Jeyarajah
Oct 17, 2009·European Journal of Cancer Care·G CormioL Selvaggi
Dec 19, 2012·Asian Pacific Journal of Cancer Prevention : APJCP·Jekaterina StankevicaSimona Donina
Jul 13, 2016·Gynecologic Oncology·Katharina PrieskeLinn Woelber
Sep 18, 2016·Critical Reviews in Oncology/hematology·L S NooijM I E van Poelgeest
May 10, 2007·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Christine BouchardyGeorges Vlastos
Jan 13, 2017·BJOG : an International Journal of Obstetrics and Gynaecology·Jkw YapD M Luesley
Feb 20, 2016·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Janine N FreyAndreas R Günthert
Oct 15, 2011·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Kate F WalkerTim Duncan
Feb 23, 2010·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Lars-Christian Horn, Stefan Wagner
Mar 5, 2009·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Xi ChengZhiyi Zhang
Mar 5, 2009·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·David K GaffneyEdward L Trimble
Jul 8, 2010·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Saskia M A GroenenCurt W Burger
Dec 18, 2009·Expert Review of Anticancer Therapy·Maaike H M OonkJoanne A de Hullu
Dec 12, 2019·Archives of Gynecology and Obstetrics·Anna JaegerLinn Woelber
May 6, 2020·Journal of Lower Genital Tract Disease·Stephanie L SkalaRichard W Lieberman
May 11, 2018·Future Oncology·San-Gang WuJuan Zhou
Mar 19, 2020·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Albert AlhatemDebra Heller
Jul 30, 2019·Case Reports in Oncological Medicine·Marta PeriMarinella Zilli
Mar 3, 2021·Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·V LancellottaL Tagliaferri
Feb 26, 2021·Clinical Nuclear Medicine·Kgomotso M G MokoalaMike M Sathekge
May 22, 2020·Journal of Gynecology Obstetrics and Human Reproduction·Florie PirotSofiane Bendifallah
Apr 28, 2020·Gynécologie, Obstétrique, Fertilité & Sénologie·E SerreUNKNOWN Groupe de Recherche FRANCOGYN

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