Patterns and problems of adult total parenteral nutrition use in US academic medical centers

Archives of Surgery
P R Schloerb, J F Henning

Abstract

To determine the pattern of total parenteral nutrition (TPN) use in US academic medical centers because TPN in adults may be associated with complications related to excessive glucose (dextrose) administration and a respiratory quotient greater than 1.0. Two surveys of the University HealthSystems Consortium (n = 106, 74 members and 32 network partners using TPN) to determine TPN formulas and amounts of TPN nutrients given to 2 hypothetical abdominal trauma patients (1 man and 1 woman), each of whom weighed 70 kg. Amounts of dextrose, amino acids, and fat and rates of administration of TPN. In the first survey, 80% (59/74) of members and 41% (13/32) of network partners of the University HealthSystems Consortium reported using TPN formulas with more than 20% dextrose; half used 25% dextrose. In the second survey, the mean (+/-SD) TPN dextrose concentrations were 190+/-43 and 170+/-45 g/L (902+/-204 and 807+/-214 mmol/L), with amino acid concentrations at 40 to 50 g/L, in the male and female patients, respectively. The amounts of amino acids and glucose given, when referred to body cell mass in the male and female patients, were equivalent. In 26% (22/86) of the institutions surveyed, the amounts of glucose given in TPN were high...Continue Reading

Citations

Nov 30, 2000·Critical Care : the Official Journal of the Critical Care Forum·C Weissman
May 4, 2011·Diabetes/metabolism Research and Reviews·Nadia Khoury, Janet B McGill
Aug 2, 2001·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·C PichardC Sierro
Jan 16, 2015·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Thomas Schricker, Ralph Lattermann
Jun 15, 2016·International Journal of Health Care Quality Assurance·Maram Gamal KatoueSamuel B Kombian
Apr 1, 2000·AORN Journal·C Drake
Dec 1, 2004·JPEN. Journal of Parenteral and Enteral Nutrition·Paul R Schloerb
May 25, 1999·JPEN. Journal of Parenteral and Enteral Nutrition·P R Schloerb, B S Skikne
Jan 19, 2000·JPEN. Journal of Parenteral and Enteral Nutrition·P R Schloerb
Jan 13, 2004·The Journal of Clinical Endocrinology and Metabolism·Dieter MesottenGreet Van den Berghe
Feb 24, 2001·Critical Care Clinics·K C McCowenB R Bistrian

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

JPEN. Journal of Parenteral and Enteral Nutrition
E B TrujilloM K Robinson
JPEN. Journal of Parenteral and Enteral Nutrition
J J PomposelliB R Bistrian
Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition
D K RosmarinJ Mirtallo
© 2021 Meta ULC. All rights reserved