Aug 15, 2014

Patterns of admixture and population structure in native populations of Northwest North America

PLoS Genetics
Paul VerduRipan S Malhi

Abstract

The initial contact of European populations with indigenous populations of the Americas produced diverse admixture processes across North, Central, and South America. Recent studies have examined the genetic structure of indigenous populations of Latin America and the Caribbean and their admixed descendants, reporting on the genomic impact of the history of admixture with colonizing populations of European and African ancestry. However, relatively little genomic research has been conducted on admixture in indigenous North American populations. In this study, we analyze genomic data at 475,109 single-nucleotide polymorphisms sampled in indigenous peoples of the Pacific Northwest in British Columbia and Southeast Alaska, populations with a well-documented history of contact with European and Asian traders, fishermen, and contract laborers. We find that the indigenous populations of the Pacific Northwest have higher gene diversity than Latin American indigenous populations. Among the Pacific Northwest populations, interior groups provide more evidence for East Asian admixture, whereas coastal groups have higher levels of European admixture. In contrast with many Latin American indigenous populations, the variance of admixture is h...Continue Reading

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  • Citations31

References

Mentioned in this Paper

Latin American
Genetic Drift
Study
Patterns
Research
Genome
Genes
DNA, Mitochondrial
African Continental Ancestry Group
Dysequilibrium Syndrome

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