PMID: 9444451Jan 28, 1998Paper

Patterns of antihypertensive use among patients in the US Department of Defense database initially prescribed an angiotensin-converting enzyme inhibitor or calcium channel blocker

Clinical Therapeutics
G J OkanoD I Brixner

Abstract

The US Department of Defense recently assembled electronic records of outpatient prescriptions dispensed through the Uniformed Services Prescription Database Project (USPDP) going back to 1990. The objectives of this portion of a larger study were: (1) to examine longitudinally the patterns of antihypertensive drug use during the first year of therapy in patients whose initial therapy was with an angiotensin-converting enzyme (ACE) inhibitor or a calcium channel blocker (CCB); (2) to determine continuous and noncontinuous users of antihypertensive drugs; and (3) to estimate the direct medication costs for each pattern of medication use. Filtering criteria for patient and prescription identification were developed, because the USPDP contains no records of confirmatory diagnoses of hypertension. Once data filters were implemented, information for 771 patients was analyzed. An ACE inhibitor was the initial therapy for 328 patients, accounting for 1935 antihypertensive medication prescription fills, and a CCB was the initial therapy for 443 patients, accounting for 2459 fills (including refills). Slightly more than half of the patients (n = 401, 52.0%) were classified as continuous users (> or = 80% medication-possession ratio [sup...Continue Reading

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Citations

Nov 7, 2002·Current Hypertension Reports·William C Gerth
Mar 25, 2008·Therapeutics and Clinical Risk Management·Nicola Fitz-SimonJohn Feely
Sep 15, 2004·PharmacoEconomics·Luca Degli Esposti, Giorgia Valpiani
Jul 31, 2013·Journal of the American Society of Hypertension : JASH·Larissa GrigoryanDavid J Hyman
Jul 26, 2006·Pharmacotherapy·J Alexander ColeAlexander M Walker
Dec 7, 2007·Clinical and Experimental Hypertension : CHE·Maria Grazia PrandinClaudio Borghi
Mar 24, 2012·American Journal of Hypertension·Larissa GrigoryanDavid J Hyman
May 31, 2002·Journal of Human Hypertension·E Degli EspostiM Volpe
Apr 1, 2004·Expert Review of Pharmacoeconomics & Outcomes Research·Krista A Payne, J Jaime Caro
Sep 6, 2007·The American Journal of Geriatric Cardiology·Michael A Weber, Nanette K Wenger
Jun 1, 2004·Expert Review of Pharmacoeconomics & Outcomes Research·Stefania LopatrielloPierfrancesco Ruffo
Nov 5, 2003·Journal of Hypertension·Judith A Whitworth, UNKNOWN World Health Organization, International Society of Hypertension Writing Group
Nov 5, 2003·Journal of Hypertension·Michael A Weber

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