PMID: 8583075Sep 1, 1995Paper

Patterns of biologic and psychologic risk factors in duodenal ulcer patients

Journal of Clinical Gastroenterology
S LevensteinG Lanari

Abstract

To clarify whether and how psychologic factors might contribute to peptic ulcer, in this study we addressed the relations between psychologic characteristics and known biologic risk factors among ulcer patients. In 75 patients with recent-onset, symptomatic duodenal ulcer, an index of three potential psychologic risk factors (stressful life events, abnormal Minnesota Multiphasic Personality Inventory, mood disturbance) was examined in relation to historical risk factors (sex, age, seasonality, family history, smoking, alcohol use, coffee consumption, nonsteroidal antiinflammatory drug use), and to blood type, serum pepsinogen I, and Helicobacter pylori antibody titers. The more risk factors in a patient's history, the less likely he or she was to have psychopathology or stress (r = -0.45, p = 0.0007). The mean number of conventional risk factors was 2.7 in patients with all three psychologic risk factors and 4.4 in patients with none; conversely, the mean number of psychologic factors was 0.9 among patients with five or more biologic risk factors and 2.1 among patients with fewer than three risk factors. This negative association was strongest among patients with no previous ulcer history. The psychologic factors also tended to...Continue Reading

Citations

Aug 2, 2007·Journal of General Internal Medicine·Sudha XirasagarChin-Shyan Chen
Nov 1, 1996·Journal of Psychosomatic Research·S LevensteinE Berto
Mar 1, 1996·Journal of Clinical Gastroenterology·S LevensteinS Spinella
Jun 1, 1996·Journal of Clinical Gastroenterology·D A Drossman
Apr 1, 1997·Journal of Clinical Gastroenterology·S LevensteinM W Smith
Mar 11, 1998·Journal of Clinical Gastroenterology·S Levenstein, G A Kaplan
Mar 27, 2002·International Journal of Epidemiology·Susan Levenstein
Apr 20, 2000·Psychosomatic Medicine·S Levenstein
Aug 12, 2014·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Susan LevensteinTorben Jorgensen
Nov 5, 1998·Journal of Oral Rehabilitation·D C McKay, L V Christensen
Jan 10, 2002·Zeitschrift für Psychosomatische Medizin und Psychotherapie·C Herrmann
Mar 7, 2021·Scientific Reports·Mi Hong YimBum Ju Lee

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