PATTERNS OF CHORIOCAPILLARIS FLOW SIGNAL VOIDS IN CENTRAL SEROUS CHORIORETINOPATHY: An Optical Coherence Tomography Angiography Study

Retina
Alexandre MatetFrancine Behar-Cohen

Abstract

To investigate choriocapillaris flow signal void distribution on optical coherence tomography (OCT) angiography in central serous chorioretinopathy (CSCR) and its correlation to choroidal vessel morphology. Fifty-three CSCR eyes (48 patients) and 34 healthy control eyes were included, retrospectively. Exclusion criteria were refractive error >2D, previous laser or photodynamic therapy, low-quality OCT angiography, or excessive shadowing artifacts. Choriocapillaris OCT angiography scans were processed by local-threshold binarization to identify signal voids, and extract their cumulative area. The locations of the two largest voids in each eye were reported on the corresponding enhanced depth imaging OCT raster scan. Choriocapillaris thickness and diameter of underlying outer choroidal vessels were measured at the level of flow voids and of adjacent outer choroidal vessels, not colocalizing with voids. There were 22 acute, 16 recurrent, and 15 chronic CSCR eyes. Total flow void area was larger in CSCR than control eyes. In univariate analysis, the total flow void area on OCT angiography increased with age (P = 0.0002), duration since CSCR diagnosis (P = 0.004), extension of autofluorescence alterations (P = 0.016), and CSCR sever...Continue Reading

References

Nov 1, 1975·The British Journal of Ophthalmology·S S Hayreh
Nov 1, 1984·The British Journal of Ophthalmology·C M GilbertS L Fine
Jan 1, 1982·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·C H von WinningB C Polak
Aug 1, 1994·Archives of Ophthalmology·D R GuyerD Orlock
Jan 1, 1995·International Ophthalmology·C Prünte
May 29, 2003·The British Journal of Ophthalmology·N KitayaA Yoshida
May 28, 2010·Investigative Ophthalmology & Visual Science·Anders PrydsMichael Larsen
Mar 15, 2011·Investigative Ophthalmology & Visual Science·Robert F MullinsJian Huang
Jun 12, 2012·The Journal of Clinical Investigation·Min ZhaoFrancine Behar-Cohen
Jul 14, 2012·Clinical & Experimental Ophthalmology·Gerald LiewSamantha Fraser-Bell
Oct 16, 2012·Retina·Sato KurodaKohji Nishida
Jun 6, 2013·Investigative Ophthalmology & Visual Science·Lihong YangWenbin Wei
Apr 24, 2014·Ophthalmology·Giovanni StaurenghiUNKNOWN International Nomenclature for Optical Coherence Tomography (IN•OCT) Panel
Jun 1, 2015·Progress in Retinal and Eye Research·Alejandra DaruichFrancine Behar-Cohen
Aug 6, 2015·Investigative Ophthalmology & Visual Science·Michel M TeussinkThomas Theelen
Oct 3, 2015·Retina·Richard F SpaideNadia K Waheed
Oct 21, 2015·Progress in Retinal and Eye Research·Daniela FerraraJay S Duker
Dec 4, 2015·Journal of Ophthalmology·Eliana CostanzoEric H Souied
Apr 12, 2016·Ophthalmic Surgery, Lasers & Imaging Retina·Nikolaus FeuchtLukas Reznicek
Jul 22, 2016·Ocular Immunology and Inflammation·Kanika AggarwalUNKNOWN OCTA Study Group
Oct 26, 2016·Scientific Reports·M A ZouacheP J Luthert
Jan 10, 2017·Retina·Alejandra DaruichFrancine Behar-Cohen
Feb 9, 2017·Retina·Richard F Spaide
Feb 9, 2017·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·Yishuang XuChangzheng Chen
Apr 7, 2017·Investigative Ophthalmology & Visual Science·Massimo NicolòCarlo Enrico Traverso
Apr 8, 2017·Investigative Ophthalmology & Visual Science·Mayss Al-SheikhDavid Sarraf
Jul 18, 2017·Investigative Ophthalmology & Visual Science·Richard F Spaide
Oct 4, 2017·Investigative Ophthalmology & Visual Science·Enrico BorrelliSriniVas R Sadda

❮ Previous
Next ❯

Citations

Apr 15, 2020·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Alexandra M CoffeyPaul A Constable
Nov 7, 2018·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Cheolmin YunJaeryung Oh
Oct 22, 2020·Vision·Gideon NkrumahJay Chhablani
Apr 3, 2020·Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society·Lucia ZiccardiMariacristina Parravano
Jun 22, 2021·American Journal of Ophthalmology Case Reports·Nicholas FowlerRamiro S Maldonado
Aug 6, 2021·Journal of Ophthalmology·Mary HoFrank Lai
Aug 1, 2021·Survey of Ophthalmology·Hamid SafiSare Safi
Aug 14, 2021·Clinical & Experimental Ophthalmology·Danny Siu-Chun NgTimothy Y Y Lai

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde
Umut Asli DincLevent Alimgil
Optometry and Vision Science : Official Publication of the American Academy of Optometry
Min KimSung Chul Lee
© 2022 Meta ULC. All rights reserved