Patterns of Glaucoma Medication Adherence over Four Years of Follow-Up

Ophthalmology
Paula Anne Newman-CaseyJoshua D Stein

Abstract

To assess longer-term patterns of glaucoma medication adherence and identify whether patterns established during the first year of medication use persist during 3 subsequent years of follow-up. Retrospective, longitudinal cohort analysis. Beneficiaries aged ≥40 years who were enrolled in a United States (US)-managed care plan for ≥7 years between 2001 and 2012 and newly diagnosed and treated for open-angle glaucoma. For each enrollee, we quantified medication adherence using the medication possession ratio. Group-based trajectory modeling (GBTM) was applied to identify patterns of adherence for 1 and 4 years of follow-up. The percent of beneficiaries who remained in the same trajectory group in the 1- and 4-year models was tabulated to evaluate group stability. Factors impacting adherence at 1 and 4 years were identified using regression analyses. Patterns of glaucoma medication adherence. Of the 1234 eligible beneficiaries, GBTM identified 5 distinct glaucoma medication adherence patterns in both the 1-year and 4-year follow-up periods. These groups were as follows: (1) never adherent after their index prescription fill (7.5% and 15.6% of persons in the 1- and 4-year models, respectively); (2) persistently very poor adherence ...Continue Reading

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Citations

May 3, 2016·Expert Review of Ophthalmology·Paula Anne Newman-CaseyAlan L Robin
Jan 13, 2018·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Najam A Sharif
Sep 12, 2018·Ophthalmic Epidemiology·Gordon T Barker, Steven L Mansberger
Dec 14, 2018·JAMA Ophthalmology·Paula Anne Newman-Casey, Jonathan S Myers
Nov 30, 2018·Asia-Pacific Journal of Ophthalmology·Tony RealiniArthur Sit
Jul 25, 2019·Journal of Cardiovascular Pharmacology and Therapeutics·Aya AjroucheFlorence Tubach
Sep 9, 2017·International Ophthalmology Clinics·Michael M LinLouis R Pasquale
Feb 23, 2020·JAMA Ophthalmology·Levi N KanuDeepak P Edward
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Sep 1, 2020·Research in Nursing & Health·Katherine A YeagerBonnie Mowinski Jennings
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Jul 31, 2019·Therapeutic Advances in Ophthalmology·Anthony T ScottAlan G Palestine
Nov 10, 2020·Veterinary Ophthalmology·Paul E Miller, Joshua Seth Eaton
Nov 12, 2020·Clinical Ophthalmology·Alan R Morse, William H Seiple
Aug 7, 2021·Ophthalmology. Glaucoma·Juno ChoPaula Anne Newman-Casey
Aug 26, 2021·Clinical Ophthalmology·Sandy KimKaranjit Kooner
Oct 29, 2021·JAMA Ophthalmology·Chiun-Ho Hou, Christy Pu

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