Patterns of invasion and routes of tumor entry into the mandible by oral squamous cell carcinoma

Head & Neck
James S BrownJ A Woolgar

Abstract

An understanding of the patterns, spread, and routes of tumor invasion of the mandible is essential in deciding the appropriate level and extent of mandibular resection in oral squamous cell carcinoma. A prospective study of histologic patterns of tumor invasion and routes of tumor entry into the mandible was performed in a consecutive series of 100 previously untreated patients. The pattern of tumor invasion of the mandible depended on the depth of invasion both in the hard (p =.001) and soft tissues (p =.001). There was evidence that the pattern of invasion was related to histologic prognostic indicators of the disease, such as extracapsular spread from invaded lymph nodes (p =.03). The route of tumor entry was at the point of abutment to the mandible (direct) in all 13 cases, invading the dentate part of the mandible. Fifty-five percent (23 of 42) of tumors invading the edentulous ridge entered through the occlusal (superior) surface. Direct entry to the mandible in the edentulous ridge was more likely for tumors arising in the tongue, floor of the mouth and the buccal mucosa compared with alveolar or retromolar sites (p =.003) Larger or more deeply invading tumors in the soft tissue are more likely to invade the mandible an...Continue Reading

References

Feb 1, 1992·The British Journal of Oral & Maxillofacial Surgery·P L LukinmaaC Lindqvist
Apr 1, 1991·International Journal of Oral and Maxillofacial Surgery·J I Cawood, R A Howell
Jan 1, 1991·Medical Hypotheses·V N Bhattathiri, M K Nair
Feb 1, 1989·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·P J Slootweg, H Müller
Aug 1, 1988·International Journal of Oral and Maxillofacial Surgery·J I Cawood, R A Howell
May 1, 1988·Head & Neck Surgery·A D McGregor, D G MacDonald
Jul 1, 1988·Head & Neck Surgery·A D McGregor, D G MacDonald
Jul 1, 1967·Oral Surgery, Oral Medicine, and Oral Pathology·S Schwartz, G Shklar
Mar 1, 1970·The British Journal of Oral Surgery·J C Southam
Oct 1, 1983·American Journal of Surgery·R L CarterH J Shaw
Sep 1, 1993·Head & Neck·A D McGregor, D G MacDonald
Dec 1, 1995·International Journal of Oral and Maxillofacial Surgery·J S Brown, R M Browne
Jun 1, 1955·A.M.A. Archives of Surgery·L T BYARS

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Citations

Sep 21, 2011·Archives of Otolaryngology--head & Neck Surgery·Ayse Tuba Karagulle KendiBevan Yueh
Feb 16, 2010·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Eric M GendenAlessandra Rinaldo
Mar 21, 2012·La Radiologia medica·S MazziottiA Blandino
Jun 14, 2012·Indian Journal of Surgical Oncology·Prashant SharmaHiren Roza
Oct 31, 2007·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Guy J PetruzzelliDarl Vandevender
Dec 10, 2003·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Guy J PetruzzelliBahman Emami
Nov 13, 2003·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Mario Fernando Muñoz GuerraJesús Sastre Pérez
Sep 30, 2003·Current Opinion in Otolaryngology & Head and Neck Surgery·James Brown
Dec 22, 2004·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Robert S RedmanLopa Mishra
Feb 1, 2007·World Journal of Surgical Oncology·Manoj PandeyB R Naik
Mar 5, 2008·Dento Maxillo Facial Radiology·D TrikeriotisD Nikolaou
Apr 1, 2014·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Chunjie LiLongjiang Li
Nov 25, 2014·Indian Journal of Surgical Oncology·Sivakumar VidhyadharanKrishnakumar Thankappan
Oct 1, 2014·Canadian Association of Radiologists Journal = Journal L'Association Canadienne Des Radiologistes·Silvio MazziottiGiorgio Ascenti
Jul 10, 2012·Biochemical and Biophysical Research Communications·Erika OueAkira Yamaguchi
Aug 11, 2012·Magnetic Resonance Imaging Clinics of North America·Mari HagiwaraBrian L Schmidt
Dec 14, 2011·Oral Oncology·Jörg HandschelKarl Christoph Sproll
Aug 23, 2011·Surgical Oncology·Latha P RaoManoj Pandey
Apr 21, 2009·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·K Alok Pathak, Bhavin C Shah
May 29, 2009·Annales d'oto-laryngologie et de chirurgie cervico faciale : bulletin de la Société d'oto-laryngologie des hôpitaux de Paris·F JegouxG Le Clech
Feb 5, 2004·International Journal of Oral and Maxillofacial Surgery·C J O'BrienG D Parker
Apr 15, 2008·International Journal of Oral and Maxillofacial Surgery·E M Van CannP J W Stoelinga
Apr 1, 2005·International Journal of Cancer. Journal International Du Cancer·Takeyuki TadaKoji Okabe
Jul 2, 2009·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Fu-Hsiung ChuangYuk-Kwan Chen
Feb 28, 2008·The Laryngoscope·Rajan S PatelChristopher J O'Brien
Aug 7, 2004·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·K A PathakM S Deshpande
Aug 30, 2005·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Kostas AntoniadesDimitris Karakasis
Sep 1, 2005·Oral Oncology·Julia Anne Woolgar, Asterios Triantafyllou
Jun 29, 2005·International Journal of Oral and Maxillofacial Surgery·T ShibaharaH Noma
Apr 6, 2004·Surgical Oncology Clinics of North America·Carsten E PalmeRalph W Gilbert
Dec 20, 2007·Oral and Maxillofacial Surgery Clinics of North America·Lee J Slater

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