Patterns of lymph node metastasis from nasopharyngeal carcinoma based on the 2013 updated consensus guidelines for neck node levels

Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology
Xiaoshen WangJianhui Ding

Abstract

To explore patterns of node distribution in nasopharyngeal carcinoma (NPC) based on the 2013 updated guidelines for neck node levels. We retrospectively reviewed the imaging documents of 3100 cases of newly diagnosed NPC between January 2010 and January 2013. All patients received an MRI scan. The scan range extended from 2 cm above the anterior clinoid process to the inferior margin of the sternal end of the clavicle. All MR images were evaluated by the multi-disciplinary treatment group of NPC. A total of 2679 (86.4%) cases had involved lymph nodes. The detailed distribution was: level Ia 0, level Ib 115 (4.3%), level IIa 1798 (67.1%), level IIb 2341 (87.4%), level III 1184 (44.2%), level IVa 350 (13.1%), level IVb 28 (1.0%), level Va,b 995 (37.1%), level Vc 49 (1.8%), level VI 0, level VIIa 2012 (75.1%), level VIIb 178 (6.6%), level VIII 53 (2.0%), level IX 2, level Xa 2, level Xb 3. Among patients with level VII involvement, only 6 (0.3%) were located at the medial group. Of the patients with level II disease, the upper borders of metastatic nodes in 25.9% cases were beyond the caudal edge of C1. Patients with level VIII, or IX, or X node metastasis were always with extensive ipsilateral lymphadenopathy, and the total numbe...Continue Reading

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Citations

Dec 27, 2015·Head & Neck·Stanley I GutiontovRuben Cabanillas
Mar 6, 2019·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Jian LiFeifei Zuo
Jul 18, 2020·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Huali MaLizhi Liu
Mar 30, 2021·Head & Neck·Wai Tong NgAlfio Ferlito
May 28, 2021·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Chaoyang JiangLing Zhang

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