Patterns of prescription and adherence to European Association of Urology guidelines on androgen deprivation therapy in prostate cancer: an Italian multicentre cross-sectional analysis from the Choosing Treatment for Prostate Cancer (CHOICE) study

BJU International
Giuseppe Morgia(Members of the LUNA Foundation, Società Italiana d'Urologia)

Abstract

To evaluate both the patterns of prescription of androgen deprivation therapy (ADT) in patients with prostate cancer (PCa) and the adherence to European Association of Urology (EAU) guidelines for ADT prescription. The Choosing Treatment for Prostate Cancer (CHOICE) study was an Italian multicentre cross-sectional study conducted between December 2010 and January 2012. A total of 1 386 patients, treated with ADT for PCa (first prescription or renewal of ADT), were selected. With regard to the EAU guidelines on ADT, the cohort was categorized into discordant ADT (Group A) and concordant ADT (Group B). The final cohort included 1 075 patients with a geographical distribution including North Italy (n = 627, 58.3%), Central Italy (n = 233, 21.7%) and South Italy (n = 215, 20.0%). In the category of patients treated with primary ADT, a total of 125 patients (56.3%) were classified as low risk according to D'Amico classification. With regard to the EAU guidelines, 285 (26.51%) and 790 patients (73.49%) were classified as discordant (Group A) and concordant (Group B), respectively. In Group A, patients were more likely to receive primary ADT (57.5%, 164/285 patients) than radical prostatectomy (RP; 30.9%, 88/285 patients), radiation t...Continue Reading

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Citations

Aug 16, 2016·Der Urologe. Ausg. A·M J Nothacker
Feb 27, 2018·The Journal of Urology·Fanny SampurnoSue Evans
Dec 31, 2019·Disease Markers·Giorgio Ivan RussoTilman Todenhöfer
Apr 4, 2018·World Journal of Urology·Roderick C N van den BerghUNKNOWN European Association of Urology Working Party on Prostate Cancer (EAU-YAUWP)
Jun 4, 2019·European Urology Oncology·Steven MacLennanJames N'Dow

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