Patterns of seizure control in patients with mesial temporal lobe epilepsy with and without hippocampus sclerosis

Arquivos de neuro-psiquiatria
A C CoanFernando Cendes

Abstract

Patients with mesial temporal lobe epilepsy (MTLE) may present unstable pattern of seizures. We aimed to evaluate the occurrence of relapse-remitting seizures in MTLE with (MTLE-HS) and without (MTLE-NL) hippocampal sclerosis. We evaluated 172 patients with MTLE-HS (122) or MTLE-NL (50). Relapse-remitting pattern was defined as periods longer than two years of seizure-freedom intercalated with seizure recurrence. "Infrequent seizures" was considered as up to three seizures per year and "frequent seizures" as any period of seizures higher than that. Thirty-seven (30%) MTLE-HS and 18 (36%) MTLE-NL patients had relapse-remitting pattern (X2, p = 0.470). This was more common in those with infrequent seizures (X2, p < 0.001). Twelve MTLE-HS and one MTLE-NL patients had prolonged seizure remission between the first and second decade of life (X2, p = 0.06). Similar proportion of MTLE-HS or MTLE-NL patients present relapse-remitting seizures and this occurs more often in those with infrequent seizures.

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Citations

Nov 5, 2015·Epilepsia·Clarissa Lin YasudaDonald William Gross
Apr 3, 2016·Clinical Neurology and Neurosurgery·Igor KuzmanovskiRozalinda Isjanovska
Jul 30, 2015·Epilepsy Research·Virginie VoltzenlogelLiliann Manning
Mar 6, 2015·Arquivos de neuro-psiquiatria·Luciano de Paola, Vera Cristina Terra
Sep 13, 2019·Postgraduate Medicine·Maria StefanatouMichael Koutroumanidis
Oct 28, 2019·Epilepsy & Behavior : E&B·Tamires Araujo ZanãoFernando Cendes

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