Patterns of skin cancer and treatment outcomes for patients with albinism at Kisangani Clinic, Democratic Republic of Congo.

International Journal of Dermatology
Gaylord InenaVictoria L Williams

Abstract

People with albinism (PWA) are at increased risk of photodamage and skin cancer. In many parts of Africa, there is a significant lack of knowledge regarding albinism which can lead to societal stigma, discrimination, and persecution from an early age. In the Democratic Republic of Congo (DRC), there is limited clinical data on PWA and skin cancer. We aim to better understand sociodemographics, risk factors, clinical features, and outcomes of this population. Patients with a diagnosis of albinism and skin cancer presenting to Kisangani Albino Clinic were enrolled. Of 205 PWA, 61 patients were diagnosed with skin cancer with a mean age of 26.5 years. Common occupations were student (45.6%) or unemployed (26.4%). Discrimination was experienced from close contacts (24.4%) and society (67.4%). A majority (88.5%) had never used sunscreen, only 4.9% used fully sun protective clothing, and 90.2% spent 4 or more hours in the sun daily. Skin cancers had a mean size of 3.8 cm and were most commonly located on the face (47.7%). Squamous cell carcinoma was the most common histopathological diagnosis. Most patients underwent excision, and 90.2% had clinical clearance of tumors at a mean follow-up of 5.7 months. People living with albinism in...Continue Reading

References

Jul 1, 1989·Clinical Genetics·J G KrombergT Jenkins
Apr 15, 1985·Cancer·J LuandeN Mohammed
Nov 6, 2007·Orphanet Journal of Rare Diseases·Karen GrønskovKaren Brondum-Nielsen
Aug 27, 2010·World Journal of Surgical Oncology·Kingsley O Opara, Bernard C Jiburum
May 17, 2012·Bulletin of the World Health Organization·Richard WoottonMaria Zolfo
Mar 7, 2014·BMC Cancer·Samson Kimaiyo KipronoHelmut Beltraminelli
Jun 13, 2015·International Health·Murray H Brilliant
Jul 15, 2015·The Pan African Medical Journal·David Kakez NdayLuboya Numbi
Nov 19, 2015·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Ann M NelsonYawale Iliyasu
May 22, 2015·African Journal of Disability·Relebohile PhatoliEleanor Ross
Jan 14, 2018·BMC International Health and Human Rights·Anita FranklinJulie Taylor
Nov 21, 2018·The Onderstepoort Journal of Veterinary Research·Davies M Pfukenyi, Samson Mukaratirwa

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Citations

Aug 20, 2021·JAAD International·Brian ChuVictoria L Williams

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