Patterns of use and appropriateness of antibiotics prescribed to patients receiving haemodialysis: an observational study

BMC Nephrology
Katrina HuiDavid C M Kong

Abstract

There are limited published data on the types and appropriateness of oral and intravenous (IV) antibiotics prescribed to patients receiving haemodialysis. This information is critical to optimise antibiotic prescribing. Therefore this study aims to describe the patterns of use and the appropriateness of oral and IV antibiotics prescribed to patients receiving haemodialysis. This was a prospective, observational study across four community and two hospital inpatient haemodialysis units in Melbourne, Australia. Data were collected from July 2014 to January 2015 from participants. Antibiotic regimens prescribed were compared with nationally available antibiotic guidelines and then classified as being either appropriate, inappropriate or not assessable by an expert multidisciplinary team using the National Antimicrobial Prescribing Survey tool. Overall, 114 participants consented to this study where 55.3% (63/114) received antibiotics and 235 antibiotic regimens were prescribed at a rate of 69.1 antibiotic regimens/100 patient-months. The most common oral antibiotics prescribed were amoxycillin/clavulanic acid and cephalexin. The most common IV antibiotics prescribed were vancomycin, piperacillin/tazobactam, cephazolin and ceftriax...Continue Reading

References

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Citations

Sep 27, 2018·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Erika M C D'AgataSophia Rosen
Jul 30, 2019·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Phillip D HahnSusan E Coffin
Mar 19, 2020·Journal of Clinical Medicine·Woldesellassie M BezabheJan Radford
May 16, 2019·Nature Reviews. Nephrology·Tina Z WangDavid P Calfee
Sep 15, 2018·The Journal of Antimicrobial Chemotherapy·Katrina HuiCarl M J Kirkpatrick
Jun 19, 2019·Seminars in Dialysis·Robert F Reilly, Nishank Jain
Dec 6, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·George N CoritsidisPremila Bhat

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