Patterns, risk factors and treatment associated with PICC-DVT in hospitalized adults: A nested case-control study

Thrombosis Research
Vineet ChopraScott A Flanders

Abstract

Peripherally inserted central catheters (PICCs) are associated with upper extremity-deep vein thrombosis (DVT). However, patterns, risk factors and treatment associated with this event remain poorly defined. To determine patterns, risk factors and treatment related to PICC-DVT in hospitalized patients. Between 2012-2013, consecutive cases of ultrasound-confirmed, symptomatic PICC-DVT were identified. For each case, at least two contemporaneous controls were identified and matched by age and gender. Patient- and device-specific data were obtained through electronic-medical records. Using variables selected a priori, multivariable logistic regression models were fit to the outcome of PICC-DVT, comparing cases to controls. 909 adult hospitalized patients (268 cases, 641 controls) were included in the study. Indications for PICC placement included long-term intravenous antibiotic therapy (n=447; 49.1%), in-hospital venous access for blood draws or infusion of medications (n=342; 44.2%), and total parenteral nutrition (n=120; 6.7%). Patients with PICC-DVT were more likely to have a history of venous thromboembolism (OR 1.70, 95% CI=1.02-2.82) or have undergone surgery while the PICC was in situ (OR 2.17, 95%CI=1.17-4.01 for surgerie...Continue Reading

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Citations

Apr 2, 2016·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·David RatzVineet Chopra
Jun 19, 2016·Journal of Vascular Surgery. Venous and Lymphatic Disorders·Jeffrey D CrawfordGregory L Moneta
Jul 1, 2017·The Journal of Vascular Access·France PaquetRichard Lindsay
Oct 23, 2018·British Journal of Nursing : BJN·Andrew BartonDennis Fitzpatrick
Jul 12, 2019·Research and Practice in Thrombosis and Haemostasis·Scott C WollerR Scott Evans
Sep 9, 2017·Journal of Infusion Nursing : the Official Publication of the Infusion Nurses Society·Britt M Meyer
Sep 4, 2020·Journal of Infusion Nursing : the Official Publication of the Infusion Nurses Society·Monica L WagnerRichard A Falcone
Apr 18, 2017·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Laura JacquesTimothy Klatt
Apr 15, 2016·Journal of Infusion Nursing : the Official Publication of the Infusion Nurses Society·Rhonda E Maneval, Bonnie J Clemence
Jul 17, 2020·The American Journal of Medicine·Tricia M KleidonVineet Chopra
May 11, 2021·Seminars in Thrombosis and Hemostasis·Hiu Lam Agnes YuenSanjeev Chunilal
Sep 22, 2020·Complementary Therapies in Medicine·Jie-Ping LiQin Li

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